合用莫沙比利与瑞巴派特在慢性萎缩性胃炎患者中的治疗有效性研究-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

合用莫沙比利与瑞巴派特在慢性萎缩性胃炎患者中的治疗有效性研究

Study on the therapeutic efficacy of Mosapride combined with ribavirin in patients with chronic atrophic gastritis

ES评分 0 浏览量：850 下载量：0

DOI	10.12208/j.ijcr.20220360
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2022, 6(8)
作者	郭芃利*,
作者单位	成都市双流区中医医院四川成都 ;
摘要	观察对慢性萎缩性胃炎患者合用莫沙比利、瑞巴派特治疗的效果。方法观察对象选择于2020.5~2022.5就诊于我院消化内科的慢性萎缩性胃炎患者90例，随机抽签法施以分组观察，施以莫沙必利单用疗法的45例患者分入对照组，施以莫沙必利、瑞巴派特合用疗法的45例患者分入试验组，观察和对比治疗效果。结果比较对照组患者，治疗有效性试验组明显较好（P<0.05）；比较对照组患者，血清炎症因子（PCT、CRP）治疗后试验组明显较好（P<0.05）；比较对照组患者，临床症状（纳差、胃胀、嗳气、恶心呕吐）消失时间试验组明显较好（P<0.05）。结论对慢性萎缩性胃炎患者合用莫沙比利、瑞巴派特治疗效果突出，在治疗有效性、血清炎症因子、转归方面优势明显，建议推广。
Abstract	Objective: To observe the effect of mosapride and ribavirin on patients with chronic atrophic gastritis. Methods: 90 patients with chronic atrophic gastritis who were treated in the Department of Gastroenterology of our hospital from May 2020 to may 2022 were selected for observation. 45 patients who were treated with Mosapride alone were divided into the control group, and 45 patients who were treated with mosapride and rebaudite were divided into the experimental group. The therapeutic effects were observed and compared. Results: compared with the patients in the control group, the treatment effectiveness of the experimental group was significantly better (p<0.05); Compared with the patients in the control group, the serum inflammatory factors (PCT, CRP) in the test group were significantly better after treatment (p<0.05); Compared with the patients in the control group, the disappearance time of clinical symptoms (anorexia, gastric distension, belching, nausea and vomiting) in the test group was significantly better (p<0.05). Conclusion: mosapride and rebaudite are effective in the treatment of patients with chronic atrophic gastritis. They have obvious advantages in treatment effectiveness, serum inflammatory factors and prognosis. It is recommended to promote them.
关键词	慢性萎缩性胃炎；莫沙比利；瑞巴派特
KeyWord	Chronic Atrophic Gastritis; Moshabili; Rebapaite
基金项目
页码	56-58

参考文献
相关文献

[1] 陈渠发,王娟,萧佩玉,等. 瑞巴派特联合莫沙比利治疗慢性萎缩性胃炎患者的临床有效性及安全性分析[J]. 北方药学,2021,18(1):29-30,33.

[2] 赵芳慧. 观察在慢性萎缩性胃炎的治疗中联用莫沙比利、瑞巴派特的有效性[J]. 中国社区医师,2021, 37(30): 48-49.

[3] 刘先秒,邓志明,连银城. 瑞巴派特联合三联疗法对慢性萎缩性胃炎患者胃肠道激素及免疫功能的影响分析[J]. 吉林医学,2020,41(11):2655-2656.

[4] 魏素英. 慢性萎缩性胃炎患者消化内科临床治疗分析[J]. 临床医药文献电子杂志,2020,7(37):53.

[5] 李小婷. 依卡倍特钠、瑞巴派特分别联合四联疗法治疗幽门螺杆菌阳性慢性萎缩性胃炎的效果及安全性观察[J]. 中国医学创新,2021,18(5):36-40.

[6] 杨艮东. 瑞巴派特片联合雷贝拉唑对慢性萎缩性胃炎患者胃功能康复及炎症反应的影响[J]. 反射疗法与康复医学,2021,2(13):74-76,80.

[7] 侯艳. 莫沙比利联合瑞巴派特治疗慢性萎缩性胃炎的临床效果及对炎症反应的影响[J]. 中华养生保健,2021,39(6):57-58.

[8] 王富华,龙丹,钟冬水. 瑞巴派特治疗老年慢性萎缩性胃炎患者的疗效及对胃动力水平和胃黏膜PGE2水平的影响[J]. 医学理论与实践,2021,34(23):4089-4091.

[9] 董瑛,陈芳,徐芳. 瑞巴派特对慢性萎缩性胃炎患者胃蛋白酶和胃泌素及炎性因子水平的影响[J]. 中国医药,2020,15(2):259-262.

[10] 张丽,张玉荣. 莫沙比利联合瑞巴派特治疗慢性萎缩性胃炎的临床效果及安全性[J]. 临床医学研究与实践,2020,5(35):81-83.

引用本文

郭芃利*. 合用莫沙比利与瑞巴派特在慢性萎缩性胃炎患者中的治疗有效性研究 [J]. 国际临床研究杂志. 2022; 6; (8). 56 - 58.

文献评论

相关学者

相关机构