Journal of International Psychiatry

【Abstract】Objective To explore the curative effect of cognitive training combined with nimodipine on cognitive function and prognosis in the treatment of acute cerebral infarction. Methods 94 cases of hospitalized acute cerebral infarction complicated with cognitive dysfunction patients of our hospital from January 2013 to May 2015 were divided into research group and control group, patients in control group were treated with nimodipine, while those in research group were cured with nimodipine combined with cognitive training. The cognitive dysfunction was evaluated with MMSE scale. Meanwhile, the prognosis was evaluated with NIHSS and CDT scales. Results: After the end of treatment, the MMSE and NIHSS scores of research group were considerably lower than control group (P<0.01), CDT score was significantly higher than control group (P<0.01). Conclusion: Cognitive training combined with nimodipine could effectively relieve the cognitive dysfunction and improve the prognosis state of acute cerebral infarction complicated with cognitive dysfunction, and promote the rehabilitation of cognitive function.

【Key words】Acute cerebral infarction; Cognitive dysfunction; Nimodipine; Cognitive training; Prognosis