首发老年抑郁症病人睡眠纺缍波、血清总胆固醇水平与抑郁、焦虑和认知功能的关系-国际精神病学杂志-CSCIED科技核心评价数据库-手机版

首发老年抑郁症病人睡眠纺缍波、血清总胆固醇水平与抑郁、焦虑和认知功能的关系

The relationship between sleep spindle waves, serum total cholesterol levels, depression, anxiety, and cognitive function in first-episode elderly patients with depression

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刊名	国际精神病学杂志 Journal of International Psychiatry
年，卷(期)	2024, 51(6)
作者	吴琼,
作者单位	长春市第六医院老年精神科
摘要	[摘要]目的：分析首发老年抑郁症病人睡眠纺缍波、血清总胆固醇（TC）水平与抑郁、焦虑和认知功能的关系。方法：选取2022年3月～2024年3月期间在我院诊治的首发老年抑郁症患者120例，采用Pearson分析睡眠纺缍波、血清TC水平与抑郁、焦虑和认知功能的相关性。结果：经Pearson分析，首发老年抑郁症患者睡眠纺缍波的数量与振幅、时长及SAS、SDS评分呈负相关（P<0.05），与密度、TC、MMSE评分呈正相关（P<0.05），首发老年抑郁症患者睡眠纺缍波的振幅与时长、SAS、SDS评分呈正相关（P<0.05），与密度、TC、MMSE评分呈负相关（P<0.05），首发老年抑郁症患者睡眠纺缍波的时长与密度、TC、MMSE评分呈负相关（P<0.05），与SAS、SDS评分呈正相关（P<0.05），首发老年抑郁症患者睡眠纺缍波的密度与TC、MMSE评分呈正相关（P<0.05），与SAS、SDS评分呈负相关（P<0.05），首发老年抑郁症患者TC与SAS、SDS评分呈负相关（P<0.05），与MMSE评分呈正相关（P<0.05），首发老年抑郁症患者SAS评分与SDS评分呈正相关（P<0.05），与MMSE评分呈负相关（P<0.05），首发老年抑郁症患者SDS评分与MMSE评分呈负相关（P<0.05）。结论：首发老年抑郁症病人的睡眠纺缍波、血清TC水平与抑郁、焦虑和认知功能密切相关。
Abstract	【Abstract】Objective：Analyze the relationship between sleep patterns, serum total cholesterol (TC) levels, depression, anxiety, and cognitive function in first-episode elderly patients with depression.Methods：Select 120 first-episode elderly patients with depression treated in our hospital from March 2022 to March 2024, and use Pearson analysis to investigate the correlation between sleep spindle waves, serum TC levels, depression, anxiety, and cognitive function.Result：According to Pearson analysis, the number of sleep spindle waves in first-episode elderly depression patients was negatively correlated with amplitude, duration, and SAS/SDS scores (P<0.05), and positively correlated with density, TC, and MMSE scores (P<0.05). The amplitude of sleep spindle waves in first-episode elderly depression patients was positively correlated with duration, SAS, and SDS scores (P<0.05), and negatively correlated with density, TC, and MMSE scores (P<0.05). The duration of sleep spindle waves in first-episode elderly depression patients was negatively correlated with density, TC, and MMSE scores (P<0.05), and positively correlated with SAS and SDS scores (P<0.05). The density of sleep spindle waves in first-episode elderly depression patients was positively correlated with TC and MMSE scores (P<0.05), and positively correlated with SAS and SDS scores (P<0.05). There was a negative correlation (P<0.05) between TC and SAS in first-episode elderly patients with depression The SDS score was negatively correlated (P<0.05) and positively correlated with the MMSE score (P<0.05). The SAS score of first-episode elderly depression patients was positively correlated with the SDS score (P<0.05) and negatively correlated with the MMSE score (P<0.05). The SDS score of first-episode elderly depression patients was negatively correlated with the MMSE score (P<0.05).Conclusion:The sleep spindle waves and serum TC levels of first-episode elderly patients with depression are closely related to depression, anxiety, and cognitive function.
关键词	[关键词]首发老年抑郁症；睡眠纺缍波；总胆固醇；抑郁；焦虑；认知功能
KeyWord	【Key words】First onset elderly depression; Sleep spinning waves; Total cholesterol; Depression; Anxiety; cognitive function
基金项目
页码	1772-1775

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吴琼. 首发老年抑郁症病人睡眠纺缍波、血清总胆固醇水平与抑郁、焦虑和认知功能的关系 [J]. 国际精神病学杂志. 2024; 51; (6). 1772 - 1775.

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