地西泮应用于口腔粘膜病患者中的效果及对不良心理状态的影响

The effect of diazepam in patients with oral mucosal disease and its influence on unhealthy mental state

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2021, 48(2)
作者
作者单位

河南省第二人民医院 ;

摘要
【摘要】 分析口腔粘膜病患者应用地西泮治疗后效果及免疫功能、焦虑抑郁情绪等指标水平变化。方法 采用随机数字表法将我院89例口腔粘膜病患者进行分组,对照组44例患者给予甘露聚糖肽治疗,观察组45例患者增加地西泮联合治疗,对比两组患者治疗后焦虑抑郁情绪、睡眠质量、免疫功能、临床疗效及不良反应发生率。结果 治疗后,观察组CD4、CD3、CD4/CD8水平及总有效率高于对照组,SAS、PSQI、SDS评分及CD8水平低于对照组,差异具有统计学意义(P<0.05);观察组患者不良反应发生率6.67%高于对照组4.55%,差异无统计学意义(P>0.05)。结论 地西泮能够有效缓解口腔粘膜病患者焦虑抑郁情绪,改善睡眠质量,联合基础治疗进一步提升机体免疫功能,提高治疗效果,安全性高。
Abstract
[Abstract] Objective To analyze the effects of diazepam in patients with oral mucosal disease after treatment, changes in immune function, anxiety, depression and other indicators. Methods A random number table method was used to group 89 patients with oral mucosal disease in our hospital, 44 patients in the control group were treated with mannan peptides, 45 patients in the observation group were treated with diazepam combination therapy, and the anxiety and depression of the two groups were compared after treatment. Mood, sleep quality, immune function, clinical efficacy and incidence of adverse reactions. Results After treatment, the observation groups CD4, CD3, CD4/CD8 level and total effective rate were higher than the control group, SAS, PSQI, SDS score and CD8 level were lower than the control group, the difference was statistically significant (P<0.05); observation group The incidence of adverse reactions in patients was 6.67% higher than that in the control group 4.55%, the difference was not statistically significant (P>0.05). Conclusion Diazepam can effectively relieve the anxiety and depression of patients with oral mucosal disease, improve sleep quality, and combine basic treatment to further improve the bodys immune function, improve the treatment effect, and have high safety.
关键词
【关键词】地西泮;口腔粘膜病;焦虑抑郁;免疫功能;睡眠质量;安全性
KeyWord
[Keywords] diazepam; oral mucosal disease; anxiety and depression; immune function; sleep quality; safety
基金项目
页码 326-329
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赵郑莉*. 地西泮应用于口腔粘膜病患者中的效果及对不良心理状态的影响 [J]. 国际精神病学杂志. 2021; 48; (2). 326 - 329.

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