The Effects of Amplitude-Based Training on Mobility, Functional Leg Strength, and Balance Confidence in Persons with Parkinson’s Disease with and Without Deep Brain Stimulation: A Case Series-Advances in Geriatric Medicine and Research-CSCIED科技核心评价数据库-手机版

The Effects of Amplitude-Based Training on Mobility, Functional Leg Strength, and Balance Confidence in Persons with Parkinson’s Disease with and Without Deep Brain Stimulation: A Case Series

The Effects of Amplitude-Based Training on Mobility, Functional Leg Strength, and Balance Confidence in Persons with Parkinson’s Disease with and Without Deep Brain Stimulation: A Case Series

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DOI	10.20900/agmr20250006
刊名	Advances in Geriatric Medicine and Research AGMR
年，卷(期)	2025, 7(2)
作者	Rosemary Lackey Babcock,Abigail Anderson,Laurie Neely*,Christina Speranza,Caitlyn Wilkerson,Jennifer Tolle,Kathleen Salik,Rolando Lazaro,Morris Casano Beato,
作者单位	Select Physical Therapy, 501 East Oak Street, Suite D, Kissimmee, FL 34744, USA ; Doctor of Physical Therapy Program, Division of Physical Therapy, School of Kinesiology & Rehabilitation Sciences ; Banner Physical Therapy in Partnership with Select Medical, 5605 Eugie Avenue, suite 215, Glendale, AZ 85304, USA ; Department of Physical Therapy, College of Health and Human Services, California State University, 6000 J Street, Sacramento, CA 95819, USA ;
摘要	Background and Introduction: As the prevalence of Parkinson’s disease (PD) increases, novel treatment methods are sought to slow the disease progression. Because medication loses effectiveness with prolonged use, deep brain stimulation (DBS) can become a surgical option. There are positive outcomes with the use of amplitude-based training (ABT) as treatment for persons with PD (PwPD), but little research has been done to support its effectiveness for individuals with DBS. Purpose: The purpose of this retrospective case series is to investigate the effects of ABT on people with and without DBS. We hypothesize that ABT will produce improvements on mobility outcomes in PwPD regardless of DBS status. Methods: Data was collected from 7 PwPD with DBS, forming the DBS+ABT group. Seven PwPD without DBS were matched based on age, gender, and ambulation status, forming the ABT group. All 14 participants received ABT following the Lee Silverman Voice Therapy BIG protocol for 16 weeks. Outcome scores to assess functional leg strength, mobility, and balance were measured pre and post intervention. A repeated measures ANOVA was performed with pre to post as the within group factor and group assignment as the between group factor. Results: No significant interaction effects were found. Significant main effects of time were found for mobility and strength outcomes. Both groups improved from pre to post, but groups did not differ. Conclusions: The findings of this study indicate that ABT may be an effective intervention to improve functional leg strength, mobility, and balance for both PwPD with and without DBS.
Abstract	Background and Introduction: As the prevalence of Parkinson’s disease (PD) increases, novel treatment methods are sought to slow the disease progression. Because medication loses effectiveness with prolonged use, deep brain stimulation (DBS) can become a surgical option. There are positive outcomes with the use of amplitude-based training (ABT) as treatment for persons with PD (PwPD), but little research has been done to support its effectiveness for individuals with DBS. Purpose: The purpose of this retrospective case series is to investigate the effects of ABT on people with and without DBS. We hypothesize that ABT will produce improvements on mobility outcomes in PwPD regardless of DBS status. Methods: Data was collected from 7 PwPD with DBS, forming the DBS+ABT group. Seven PwPD without DBS were matched based on age, gender, and ambulation status, forming the ABT group. All 14 participants received ABT following the Lee Silverman Voice Therapy BIG protocol for 16 weeks. Outcome scores to assess functional leg strength, mobility, and balance were measured pre and post intervention. A repeated measures ANOVA was performed with pre to post as the within group factor and group assignment as the between group factor. Results: No significant interaction effects were found. Significant main effects of time were found for mobility and strength outcomes. Both groups improved from pre to post, but groups did not differ. Conclusions: The findings of this study indicate that ABT may be an effective intervention to improve functional leg strength, mobility, and balance for both PwPD with and without DBS.
关键词	LSVT; falls; progressive disease; matched-control; strength; balance; physical therapy
KeyWord	LSVT; falls; progressive disease; matched-control; strength; balance; physical therapy
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Rosemary Lackey Babcock,Abigail Anderson,Laurie Neely*,Christina Speranza,Caitlyn Wilkerson,Jennifer Tolle,Kathleen Salik,Rolando Lazaro,Morris Casano Beato. The Effects of Amplitude-Based Training on Mobility, Functional Leg Strength, and Balance Confidence in Persons with Parkinson’s Disease with and Without Deep Brain Stimulation: A Case Series [J]. Advances in Geriatric Medicine and Research. 2025; 7; (2). - .

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