Journal of International Psychiatry

Schizophrenia is a serious chronic mental disease, which causes serious family and social burdens. However, the molecular pathogenesis of schizophrenia is still unclear. Studies have found that there are changes in the gut microbiota of patients with schizophrenia and that this change is correlated with the development of schizophrenia. Changes in the composition and quantity of gut microbiota can contribute to the occurrence of schizophrenia by causing the abnormality of the nervous system development, metabolic dysfunction, and immune system disorders through the brain-gut axis. This article reviews the role of gut microbiota in schizophrenia.

Gut microbiota；Schizophrenia；Brain-gut axis