Journal of International Psychiatry

Major depressive disorder (MDD),as a common emotional disorder in adolescents, is one of the main causes of adolescent suicide. More and more studies have shown that there are multimodal imaging abnormalities of central nervous system in adolescents with depression and suicide behaviors associated with NSSI. However, there are few studies on magnetic resonance spectroscopy in this field, and there is no consistent conclusion about its neurobiological mechanism. Therefore, this paper summarizes the relevant literature at home and abroad in recent years, in order to find specific brain imaging markers that can accurately predict adolescent depressive disorder and its potential suicide risk, and provide effective reference and new clues for further research in the future.

Adolescents with depression；suicide；Magnetic resonance spectroscopy(MRS)