Journal of International Psychiatry

Abstract Objective: To study the escitalopram combined with insulin therapy in diabetic patients with anxiety and depression in patients with clinical effect. Methods: 80 patients in our hospital anxiety and depression from May 2014 to June 2015 were treated with diabetes, using the random number table 80 patients with diabetes, patients with symptoms of anxiety and depression were divided into observation group (40 cases) and the control group (40 cases); the control group received conventional insulin therapy, the observation group taking escitalopram treatment on the basis of the control group, two groups were observed and compared the clinical effectiveness, HAMD score, HAMA score and postprandial 2h glucose and glycated hemoglobin. Results: The clinical observation group was 87.50% higher than the efficiency of 67.50% (P <0.05); observation group HAMD score and HAMD score was significantly lower than the control group (P <0.05); postprandial blood glucose 2h observation group and saccharification hemoglobin were lower than the control group (P <0.05). Conclusion: escitalopram in patients with diabetes and insulin treatment of anxiety and depression have a significant clinical effect, reduce the patients negative emotions, so that blood glucose levels are effectively controlled, and therefore worthy of further clinical application.

Key words: escitalopram; insulin; diabetes; anxiety and depression; clinical effect临床上