疏肝消痹方联合氟西汀治疗乳腺癌合并抑郁的疗效探析

Research on treatment of fluoxetine and Shuganxiaobi prescription for breast cancer in depression

ES评分 0

DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(1)
作者
作者单位

陕西省咸阳市礼泉县人民医院外三科 ;
第四军医大学西京医院血管内分泌外科 ;
西安市新城区长乐路127号 ;

摘要
【摘要】目的:探析氟西汀、中医疏肝消痹方联合方案对于乳腺癌合并抑郁(breast cancer in depression, BCID)的临床治疗效果。方法:选择我院收治的BCID患者84例,所选患者均接受乳腺切除术及术后全身化疗辅助治疗(CMF化疗方案),采用随机数表法将其分成两组给药抗抑郁药物,联合组42例服用疏肝消痹方+氟西汀、对照组42例服用氟西汀,对比给药前后两组患者的抑郁症状改善情况、乳腺癌实验室指标以及综合疗效。结果:(1)给药前,两组患者的汉密尔顿抑郁评分(HAMD总评分)差异无统计学意义(P>0.05),给药1疗程后,联合组的HAMD总评分显著低于对照组(P<0.05);(2)在实验室特异标记物检验结果方面,给药前,两组的CA15-3、CEA、CA125水平差异无统计意义(P<0.05),给药1疗程后,联合组的CA15-3、CEA、CA125水平均显著低于对照组(P<0.05);(3)在综合疗效上,联合组的显效率、总好转率均显著高于对照组(P<0.05)。结论:氟西汀联合中医疏肝消痹方不仅能够有效改善患者的抑郁症状,还能对乳腺癌起到辅助治疗效果,该方案治疗BCID的综合疗效良好、值得推广和应用。
Abstract
【Abstract】AIM: To analyze the treatment effect of fluoxetine with Shuganxiaobifang for breast cancer in depression .MRTHODS: During May,2014 to May,2015,84 cases of patients with breast cancer in depression were randomly made into Joint Group(42 cases,treated with fluoxetine and Shuganxiaobi prescription)and Control Group(42 cases,treated with fluoxetine),and their HAMD scores and treatment effect were compared.RESULTS:Before and after treatment, to improve the level of the joint group HAMD score, CA15-3, CEA, CA125 and other indicators and integrated efficacy were significantly better than the control group (P <0.05)CONCLUSION: Fluoxetine joint Chinese medicine Shugan Xiaobi party not only can improve the symptoms of depression, but also to play a supporting breast cancer treatment, good overall efficacy of the regimen BCID worthy of promotion and application.
关键词
【关键词】疏肝消痹方+氟西汀;BCID;综合疗效;临床探析
KeyWord
【Keywords】Shuganxiaobi prescription+fluoxetine;BCID; Treatment effect;Research
基金项目
页码 116-118
  • 参考文献
  • 相关文献
  • 引用本文

常继业*,王廷,张伟东,王锋. 疏肝消痹方联合氟西汀治疗乳腺癌合并抑郁的疗效探析 [J]. 国际精神病学杂志. 2017; 44; (1). 116 - 118.

  • 文献评论

相关学者

相关机构