乌灵胶囊结合帕罗西汀治疗癫痫伴抑郁症的临床效果观察

The clinical effect of the treatment epilepsy with depression by Wu Ling Capsule Combined with PaRossi Dean.

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2016, 43(1)
作者
作者单位

威阳市第一人民医院神经内科 ;

摘要
研究癌病合并幸F郁症患者应用鸟灵胶表联合帕罗西、1了治疗的临床效果。 方法选取我院从2013年3月至2014年7月收治的病病合并幸F郁症患者80例, 采用随机数字表法将80例癌病合并1中郁症患者分为观察组(40例) 和对照组(40例) ; 对照组采取帕罗西、1丁进行治疗,观察组采取鸟灵胶愛联合帕罗西⊠丁进行治疗,将两组患者的 HAMD评分、 PHQ-9评分、临床有效率以及不良反应发生率进行对比分析。 结果 将两组患者的临床有效率进行统计, 观蔡组为95. 00%, 对照组为80. 00%, 观蔡组的临床有效率明显高于对照组, 纽间比较差异具有统计学意义(」P<0.05);观察组与对照组的 HAMD评分与 PHQ-9评分比较差异具有统计学意义(P< 0. 05) ; 治疗过程中患者发生的不良反应有头晕、 嗜睡、 心慌、 水月中以及乏力, 其中观察组的不良反应发生率为15.00%,对照组的不良反应发生率为30.00%,组间比较差异无统计学意义(P> 0. 05) 。 结论 乌灵胶愛联合帕罗西r治疗病病合并幸F郁症患者临床效果显著, 且1F郁症状与癌病症状均得到有效的改善, 不增加不良反应发生率, 因此临床值得进一步推广 。
Abstract
〇bjective To study the clinical effect and effectiveness of the combination of the treatment of thepatients with epilepsy and depression by using Wu Ling Capsule and Pa Rossi Dean. Methods From March2013 to July2014, 80 paLients with epilepsy were Lreated with epilepsy, 80 cases of epilepsy wiLh depression were random- ly divided into observation group(40 cases) and control group(40 cases); the control group was treated by Pa Rossi Dean, the HAMD score, PHQ-9 score, clinical efficacy and adverse reactions were compared between the two groups. Results The two groups of patients, the clinical efficiency of statistics, the observation group is95%, the control group was80.00% in the observation group, the clinical efficiency was significantly higher than that of the control group, the difference between the two groups has statistical significance(P<0.05) ; observation group and control group of HAMD and PHQ-9 scores than is the difference was statistically significant(P<0.05) ; in the course of treatment in patients with adverse reactions with and drowsiness, dizziness, palpitation, edema and fatigue, which in the observation group, the adverse reacLion occurrence rate Isl5.00%, control group of adverse reactions occur rate was30. 00%, Lhe between group difference no staLisLical significance(P<0. 05). Conclusion The clini- cal effect of the combined treatment of the patients with epilepsy combined with depression was significant, and the symptoms of depression and symptoms of depression were significantly improved, and it can also reduce the occur_ roneo of seizures, and not increase the incidence of adverse reactions, so the clinical value was further promoted by Pa Rossi Dean.
关键词
癫痫;抑郁症;乌灵胶囊;帕罗西汀;临床效果
KeyWord
Epilepsy; Depression; Wu Ling Capsule; Pa Rossi Dean; Clinical effect
基金项目
页码 109-112
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赵锦华*, 李文强,鱼丽萍,康永刚. 乌灵胶囊结合帕罗西汀治疗癫痫伴抑郁症的临床效果观察 [J]. 国际精神病学杂志. 2016; 43; (1). 109 - 112.

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