注意缺陷多动障碍患者一级亲属的注意功能研究

Study of attention functions in the first degree relatives of children with symptoms of attention- deficit/hyperactivity disorder.

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2016, 43(2)
作者
作者单位

山东省聊城市第四人民医院 ;

摘要
目的 探讨注意缺陷多动障碍(attention- deficit/ hyperactivity disorder,ADHD)患者一级亲属的注意功能特点。方法 将80例ADHD患者一级亲属(first degree relative,FDR)及与其人口学资料相匹配的80例健康对照(healthy controls,HC)组采用连线测试、Stroop色词测试,GO/No-go任务进行注意功能测定。结果 FDR组在连线测试-B反应时、GO/No-go任务反应时与错误数,Stroop-C反应时[分别为(89.98±23.77)s,(1172.41±427.16)ms,(2.25±2.05)次,(1114.15±463.02)ms]差于HC组[分别为(983.50±13.51)s,(834.66±306.52)ms,(1.63±1.47)次,(1006.51±338.92)ms],差异有统计学意义(分别t =2.118,P =0.018;t =5.752,P <0.001;t =2.214,P =0.014;t =1.678,P =0.048)。结论 ADHD患者一级亲属有不同程度的注意功能损害。
Abstract
Objective To explore attention functions in the first degree relatives of attention-deficit/hyperactivitydisorder(ADHD)patients. (ADHD)patients. ADHD)patients. )patients. patients. Methods A total of 80 first degree relatives of ADHD patients (FDRgroup)and80healthy (FDRgroup)and80healthy FDR group)and80healthy )and80healthy and 80 healthycontrols(HC)enrolledthisresearch. All of thesubjects’sattentionfunctionwereassessedbyTrail Makingtest、 (HC)enrolledthisresearch. All of thesubjects’sattentionfunctionwereassessedbyTrail Makingtest、 HC)enrolledthisresearch. All of thesubjects’sattentionfunctionwereassessedbyTrail Makingtest、 )enrolledthisresearch. All of thesubjects’sattentionfunctionwereassessedbyTrail Makingtest、 enrolled this research. All of the subjects’s attention function were assessed by Trail Making test、Stroop colour-word Test,GO/No-goTest. ,GO/No-goTest. GO/No-go Test. Results Compared with HC group [(83.50±13.51)s,(834.66±306.52) [(83.50±13.51)s,(834.66±306.52) 83.50±13.51)s,(834.66±306.52) )s,(834.66±306.52) s,(834.66±306.52) ,(834.66±306.52) 834.66±306.52)ms,(1.63±1.47)time,(1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) ,(1.63±1.47)time,(1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) 1.63±1.47)time,(1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) )time,(1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) time,(1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) ,(1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) 1114.15±463.02)msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) )msrespectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) ms respectively],FDRgroup[(89.98±23.77)s,(1172.41±427.16) ],FDRgroup[(89.98±23.77)s,(1172.41±427.16) FDR group[(89.98±23.77)s,(1172.41±427.16) [(89.98±23.77)s,(1172.41±427.16) 89.98±23.77)s,(1172.41±427.16) )s,(1172.41±427.16) s,(1172.41±427.16) ,(1172.41±427.16) 1172.41±427.16)ms,(2.25±2.05)time,(1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction ,(2.25±2.05)time,(1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction 2.25±2.05)time,(1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction )time,(1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction time,(1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction ,(1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction 1006.51±338.92)msrespectively]showedsigniflcantlyimpairedinperformanceof reaction )msrespectively]showedsigniflcantlyimpairedinperformanceof reaction ms respectively]showedsigniflcantlyimpairedinperformanceof reaction ]showedsigniflcantlyimpairedinperformanceof reaction showed signiflcantly impaired in performance of reactiontime of Trail Making test-B、reactiontimeanderrornumberof GO/No-goTest,reactiontimeof Stroop-C( 、reactiontimeanderrornumberof GO/No-goTest,reactiontimeof Stroop-C( reaction time and error number of GO/No-go Test,reactiontimeof Stroop-C( ,reactiontimeof Stroop-C( reaction time of Stroop-C(t =2.118,P =0.018;t =5.752,P <0.001;t =2.214,P =0.014;t =1.678,P =0.048 respectively). ). Conclusion The first degreerelatives of ADHD patient exhibited attention impairment.
关键词
注意缺陷多动障碍;认知;注意
KeyWord
Attention-deficit/hyperactivity;Cognition;Attention ;
基金项目
页码 200-202
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张君*,赵长印,张莉莉,崔玉霞. 注意缺陷多动障碍患者一级亲属的注意功能研究 [J]. 国际精神病学杂志. 2016; 43; (2). 200 - 202.

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