Journal of International Psychiatry

Abstract】Ojective To study the related dangerous factors of cerebral microbleeds and cognitive dysfunction.Methods 280 patients with transient ischemic attack and lacunar infarct treated in our hospital from March 2013 toMarch 2015 were retrospectively studied and selected to be divided into 2 groups according to Montreal Cognitive As-sessment（MoCA）score，and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ （MoCA）score，and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ MoCA）score，and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ ）score，and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ score，and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ ，and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ and180cases’score≥26wasregardedasthenormal group，whileanother100cases’ 180cases’score≥26wasregardedasthenormal group，whileanother100cases’ 180 cases’ score ≥ 26 was regarded as the normal group，whileanother100cases’ ，whileanother100cases’ while another 100 cases’score <26waslookedastheabnormal group. Therelateddangerousfactorsof cerebral microbleedsandcognitivedys- <26waslookedastheabnormal group. Therelateddangerousfactorsof cerebral microbleedsandcognitivedys- 26 was looked as the abnormal group. The related dangerous factors of cerebral microbleeds and cognitive dys-function was analyzed. Results Single factor analysis showed difference in the cases of positive CMB，theamount of ，theamount of the amount ofCMB，theeducationtimeandleukoaraiosiscaseshadstatisticalsignificance（ ，theeducationtimeandleukoaraiosiscaseshadstatisticalsignificance（ the education time and leukoaraiosis cases had statistical significance（P <0.05）. Logisticregressionanalysisof ）. Logisticregressionanalysisof . Logistic regression analysis ofthe influence factors to patients demonstrated cases of positive CMB，thenumberofCMBandtheeducationtime’sOR ，thenumberofCMBandtheeducationtime’sOR the number of CMB and the education time’s ORvalue was 4.57，1.44，0.71respectively（ ，1.44，0.71respectively（ 1.44，0.71respectively（ ，0.71respectively（ 0.71 respectively（P <0.05）. ）. Conclusion Positive CMB and the number of it was the risk fac-tors of cognitive dysfunction，coexistedwithothercrebrovasculardiseases. ，coexistedwithothercrebrovasculardiseases. coexisted with other crebrovascular diseases.

】 Key words】 Cognitive dysfunction；Cerebralmicrobleeds；MontrealCognitiveAssessment；Lacunarinfarction ；Cerebralmicrobleeds；MontrealCognitiveAssessment；Lacunarinfarction Cerebral microbleeds；MontrealCognitiveAssessment；Lacunarinfarction ；MontrealCognitiveAs