Journal of International Psychiatry

Abstract】Objective To research curative effect of individual whole course intervention indepression patientswith psychotic symptoms. Methods 81 patients with psychotic symptoms of depression were divided into research group（n =39）andcontrol group（ ）andcontrol group（ and control group（n =42），andthenthepatientsinresearchgroupweregiventhewholecourseinterven- ），andthenthepatientsinresearchgroupweregiventhewholecourseinterven- and then the patients in research group were given the whole course interven-tion while the control group with conventional treatment. After that，Brief PsychiatricRatingScale（BPRS），Hamilton ，Brief PsychiatricRatingScale（BPRS），Hamilton Brief Psychiatric Rating Scale（BPRS），Hamilton （BPRS），Hamilton BPRS），Hamilton ），Hamilton HamiltonDepression Scale（HAMD），general qualityof lifeinventory（GQOLI-74）andTreatment Emergent SymptomScale （HAMD），general qualityof lifeinventory（GQOLI-74）andTreatment Emergent SymptomScale HAMD），general qualityof lifeinventory（GQOLI-74）andTreatment Emergent SymptomScale ），general qualityof lifeinventory（GQOLI-74）andTreatment Emergent SymptomScale general quality of life inventory（GQOLI-74）andTreatment Emergent SymptomScale （GQOLI-74）andTreatment Emergent SymptomScale GQOLI-74）andTreatment Emergent SymptomScale ）andTreatment Emergent SymptomScale and Treatment Emergent Symptom Scale（TESS）wereusedtoevaluatethetherapeuticeffectoftwogroupsincourseoftreatmentofthebeginning，3months，6 TESS）wereusedtoevaluatethetherapeuticeffectoftwogroupsincourseoftreatmentofthebeginning，3months，6 ）wereusedtoevaluatethetherapeuticeffectoftwogroupsincourseoftreatmentofthebeginning，3months，6 were used to evaluate the therapeutic effect of two groups in course of treatment of the beginning，3months，6 ，3months，6 3 months，6 ，6months and 1 year，respectively. ，respectively. respectively. Results The score of two groups in（BPRS），（HAMD），（GQOLI-74）andshowedno （BPRS），（HAMD），（GQOLI-74）andshowedno BPRS），（HAMD），（GQOLI-74）andshowedno ），（HAMD），（GQOLI-74）andshowedno HAMD），（GQOLI-74）andshowedno ），（GQOLI-74）andshowedno GQOLI-74）andshowedno ）andshowedno and showed noobvious differences（P >0.05）intheverybeginning，but afterthree，six，and1yearof treatment. Thescorebetween ）intheverybeginning，but afterthree，six，and1yearof treatment. Thescorebetween in the very beginning，but afterthree，six，and1yearof treatment. Thescorebetween ，but afterthree，six，and1yearof treatment. Thescorebetween but after three，six，and1yearof treatment. Thescorebetween ，six，and1yearof treatment. Thescorebetween six，and1yearof treatment. Thescorebetween ，and1yearof treatment. Thescorebetween and 1 year of treatment. The score betweenthe two groups in each scale had a significant（P <0.05）andaobviousdifference（ ）andaobviousdifference（ and a obvious difference（P <0.01）. ）. Conclusions Individual-ized whole course intervention can effectively relieve the symptoms in depression patients with psychotic，improvethe ，improvethe improve thepatients social function，healthstatus，qualityoflife，themedicationcomplianceandreemploymentrate，reducethe ，healthstatus，qualityoflife，themedicationcomplianceandreemploymentrate，reducethe health status，qualityoflife，themedicationcomplianceandreemploymentrate，reducethe ，qualityoflife，themedicationcomplianceandreemploymentrate，reducethe quality of life，themedicationcomplianceandreemploymentrate，reducethe ，themedicationcomplianceandreemploymentrate，reducethe the medication compliance and reemployment rate，reducethe ，reducethe reduce therecurrence rate.

Whole course intervention；Psychoticsymptoms；Depression；Curativeeffect