精神分裂症患者药源性肠梗阻临床分析

Clinical Analysis of Drug-derived Ileus in Patients with Schizophrenia.

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2016, 43(2)
作者
作者单位

天津市安定医院 ;

摘要
目的 分析住院精神分裂症患者发生药源性肠梗阻的临床特点及危险因素。方法 采用回顾性研究,对本院3363例住院精神分裂症患者临床资料进行分析,并对8项观察指标进行单因素和Logistic回归分析。结果 3363例精神分裂症患者中84例(2.50%)发生肠梗阻,Logistic回归分析提示年龄>60岁、住院时间>90天、服用氯氮平、用药时间>5年、服用安坦及腹部手术史是精神分裂症患者肠梗阻的独立危险因素(P <0.05)。结论 住院精神分裂症患者合并肠梗阻的危险因素多,临床应根据这些危险因素积极预防。
Abstract
Objective To analyze the clinical features and risk factors of ileus in patients with schizophrenia,then propose preventive measures. Methods Clinical data were retrospectively reviewed in 3363 hospitalized patientswho with schizophrenia. 8 variables were included to statistical analysis using univariate analysis and Logistic regressionanalysis. Results Among 3363 cases,84(2,50%)caseswerewithileus. Logisticregressionanalysisshowedthat ,84(2,50%)caseswerewithileus. Logisticregressionanalysisshowedthat 84(2,50%)caseswerewithileus. Logisticregressionanalysisshowedthat (2,50%)caseswerewithileus. Logisticregressionanalysisshowedthat 2,50%)caseswerewithileus. Logisticregressionanalysisshowedthat ,50%)caseswerewithileus. Logisticregressionanalysisshowedthat 50%)caseswerewithileus. Logisticregressionanalysisshowedthat %)caseswerewithileus. Logisticregressionanalysisshowedthat cases were with ileus. Logistic regression analysis showed thatpatient’s age>60,lengthof hospital stay>90d,takingclozapine,treatment time>5y,takingAntinandahistoryof ,lengthof hospital stay>90d,takingclozapine,treatment time>5y,takingAntinandahistoryof length of hospital stay>90d,takingclozapine,treatment time>5y,takingAntinandahistoryof ,takingclozapine,treatment time>5y,takingAntinandahistoryof taking clozapine,treatment time>5y,takingAntinandahistoryof ,treatment time>5y,takingAntinandahistoryof treatment time>5y,takingAntinandahistoryof ,takingAntinandahistoryof taking Antin and a history ofabnominal sugury were independent risk factors for ileus in patients with schizophria(P <0.05). ). Conclusion There aremany risk factors in schizophrenia with ileus. To prevent ileus in clinical work,wehavetointervenetheseriskfactors ,wehavetointervenetheseriskfactors we have to intervene these risk factorsearly.
关键词
精神分裂症;肠梗阻;氯氮平
KeyWord
Schizophrenia;Ileus;Clozapine;
基金项目
页码 313-314
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刘春英*,庞继松,任丽娜,张晓菲. 精神分裂症患者药源性肠梗阻临床分析 [J]. 国际精神病学杂志. 2016; 43; (2). 313 - 314.

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