Journal of International Psychiatry

【Abstract】 Objective To investigate the effects of community based integrated medicine management model on patients with schizophrenia, and provide evidence to improve the quality of community based mental health service. Method 100 patients was enrolled and allocated into intervention group and general control group (50 for each group). A blanket of instruments include positive and negative symptom scales (PANSS), social function deficit screening scale (SDSS), and self-knowledge and treatment attitude questionnaires (ITAQ) were administrated at baseline, after 6 months and after 12 months. Repeated variance analysis employed to detect the effects at different time. Results There were no significant difference of the scores of instruments assessed at baseline. Those patients in intervention group had significant lower total score of PANSS, positive scale, and negative scale than patients in control group after six months (49.30±11.67 vs 61.12±17.48，9.24±3.44 vs 12.72±5.95, 14.02±3.78 vs 16.58±6.98), respectively. Those patients in intervention group had significant lower total score of PANSS, positive scale, and negative scale than patients in control group after twelve months (44.68±8.47 vs 57.86±16.08，8.12±2.24 vs 11.26±5.36, 12.86±3.25 vs16.24±6.88), respectively. The repeated variance analysis showed significant reduction of total score of PANSS, positive scale, negative scale, and SDSS in intervention group under controlling of time variable (P<0.05). There were no significant reduction of the score of ITAQ. Conclusion In the area where the network of community health care facilities is well-developed, the implementation of the seamless connection mode of community medication management is effective and feasible for patients with schizophrenia.

community medication; seamless connection; schizophrenia; PANSS