| Abstract |
[Abstract] Objective To explore the relationship between intraoperative cerebral oxygen saturation (rSO2) changes and postoperative cognitive dysfunction in elderly patients undergoing cardiac surgery. Methods A total of 100 elderly patients undergoing cardiopulmonary bypass surgery from June 2018 to January 2021 were selected. Local rSO2 was monitored during the operation, and cognitive dysfunction screening was performed 1 week after surgery. The baseline value of rSO2, the lowest value (rSO2min), the rate of change of rSO2, and general perioperative data between the two groups of patients were compared. Univariate and multivariate logistic regression analysis were used to investigate the relationship between intraoperative changes of rSO2, perioperative data and postoperative cognitive dysfunction. Results Forty-four cases of cognitive dysfunction occurred in 100 elderly patients undergoing cardiac surgery, with an incidence rate of 44.00%. Univariate analysis showed that there were statistically significant differences in the rate of change of rSO2min, rSO2 change rate, cardiopulmonary bypass time, age, postoperative atrial fibrillation, and preoperative cardiac function classification between the cognitive dysfunction group and the non-cognitive dysfunction group (P<0.05). There was no significant difference in gender, rSO2 baseline value, and type of surgery between the two groups (P>0.05). Multivariate logistic regression analysis showed that rSO2min<57%, rSO2 change rate>30%, cardiopulmonary bypass time>40min, age>70 years old are risk factors for postoperative cognitive dysfunction in elderly patients undergoing cardiac surgery. Conclusion The low content of rSO2 and large change rate in elderly patients undergoing cardiac surgery are risk factors for postoperative cognitive dysfunction, and cognitive dysfunction is also related to factors such as cardiopulmonary bypass time and age.
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