高盐饮食对肾脏的影响-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

高盐饮食对肾脏的影响

The effect of high-salt diet on the kidney

ES评分 0 浏览量：804 下载量：0

DOI	10.12208/j.ijcr.20220302
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2022, 6(7)
作者	刘星星*,李丽丹,王斌鑫,吕锦彬,
作者单位	新疆第二医学院新疆克拉玛依 ;
摘要	高盐饮食的摄入是导致高血压发病的重要因素之一。在高血压防治中必须强调限盐饮食，从而减小高血压所致靶器官损害。作为高盐的靶器官-肾脏，高盐对肾脏的危害更是不可小视，同时高盐对肾脏生理结构病理性改变的机制、影响也正在被逐渐挖掘，这些调查、研究都将为临床诊疗活动提供充分、有力的依据。而随着调查、研究的不断地深入，高盐对心血管疾病、乃至靶器官的直接、间接影响也正在浮出水面。将食盐摄入量与血压和肾脏疾病联系起来的文献支撑也越来越多，而且越来越突出。
Abstract	The intake of high salt diet is one of the important factors leading to hypertension. Salt restriction diet must be emphasized in the prevention and treatment of hypertension so as to reduce the target organ damage caused by hypertension. As the target organ of high salt -- kidney, the harm of high salt to kidney is not to be underestimated. Meanwhile, the mechanism and influence of high salt on the pathological change of kidney physiological structure are also being gradually explored. These investigations and studies will provide sufficient and powerful basis for clinical diagnosis and treatment activities. With the deepening of investigation and research, the direct and indirect effects of high salt on cardiovascular diseases and even target organs are emerging. The literature linking salt intake to blood pressure and kidney disease is growing and its influence is becoming more prominent.
关键词	高盐饮食；肾脏；高血压
KeyWord	High-Salt Diet; Kidney; Hypertension
基金项目
页码	42-44

参考文献
相关文献

[1] Joint, Committee, for, et al. 2018 Chinese Guidelines for Prevention and Treatment of Hypertension-A report of the Revision Committee of Chinese Guidelines for Prevention and Treatment of Hypertension[J]. Geriatr Cardiol, 2019, 16(3):182-241.

[2] 吴兆苏,霍勇,王文,等.中国高血压患者教育指南［J］.慢性病学杂志,2014,15(1):1-30

[3] WeinbergerMH,FinebergNS,FinebergSE,etal.:Saltsensitivity,pulsepres-sure, and death in normal and hypertensive humans. Hypertension 2001,37(part 2):429–432.

[4] 丁丽红. 蛋白尿引起肾小管间质损伤新机制[D].东南大学,2015.

[5] DAVID LONG, KAREN PRICE, JAIME HERRERA ACOSTA, et al. How Does Angiotensin II Cause Renal Injury?[J]. Hypertension: Journal of The American Heart Association, 2004,43(4):722-723.

[6] Okada H et al. Osteopontin expressed by renal tubular epithelium mediates interstitial monocyte infiltration in rats.[J]. American journal of physiology. Renal physiology, 2000, 278(1) : F110-21.

[7] Sakai T, Tanaka H, Shirasawa. Two distinct epithelial responses may compensate for the ureteral obstruction in early and late phase of unilateral ureteral obstruction- treated rat: cellular proliferation in acute phase and osteopontin expression in chronic phase. Nephron, 1997，77：340-345.

[8] 郑勇,刘治全,叶涛,等. 高盐对AngⅡ肾损伤SD大鼠血压、肾脏组织形态及骨调素表达的影响[J].第一军医大学学报,2005,25(7):827-832.

[9] Lan HY, Yu XQ, Yang NS, et al. De novo glomerular osteopontin expression in rat crescentic glomerulone- phritis. Kidney Int 1998，53：136-145.

[10] M1 and M2 Macrophages: Oracles of Health and Disease [J]. Critical Reviews in Immunology, 2013, 32(6): 463-488.

[11] Sanders, P. W. , et al. "Increased dietary salt accelerates chronic allograft nephropathy in rats." Kidney International 59.3(2001):1149-1157.

[12] Jerome D E, Yum V, Skelton M M, et al. Hypertension induces proteinuria and renal fibrosis associated with endoplasmic reticulum (ER) stress in the Dahl salt sensitive rat[J]. The FASEB Journal, 2012, 26(S1).

[13] 陆静,白志勋,匡晓燕,等. 高盐刺激可诱导巨噬细胞极化从而促进肾脏成纤维细胞的增殖及表型转化[J]. 南方医科大学学报,2020,40(10):1472-1479.

[14] 夏南,张焕鑫,赵继先,等. 高盐饮食对自发性高血压大鼠肾脏的影响及左旋氨氯地平的作用[J]. 中国循证心血管医学杂志,2019,11(5):611-613,617.

[15] Su G,Mi S,Tao H,et al. Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes[J]. Cardiovasc Diabetol,2011, 10:19.

[16] 刘春,李卫,缪进,朱顺星,邵义祥.高盐饮食对小鼠心肝肾的影响[J].现代预防医学,2010,37(24):4653-4654.

[17] 任洁,胡经文,郭统帅,何明俊,刘富强,牟建军.高盐饮食对盐敏感性高血压大鼠肾脏损伤的影响[J].安徽学,2020, 41(08): 872-875.

[18] 韦宏，贾静，杨庆辉，等．肾脏去交感神经支配术在心衰治疗中的作用［J］．现代生物医学进展，2013，13( 13) : 207 －210．

[19] 陈丽萌，黄宇宁，秦岩．血管紧张素Ⅱ调节肾脏球旁器颗粒细胞合成肾素的机制研究［J］．中华肾脏病杂志，2010，26(1):28－33．

[20] 毛佳泉,李学英,樊军佑,等. 高盐饮食致SD大鼠高血压及对其心血管和肾脏影响[J]. 甘肃科技,2020,36(12): 56-58,37.

[21] 戎亦骊,潘永明,黄俊杰,等.高脂高盐饮食诱导巴马小型猪高血压模型的建立及其机制探讨[J].中国实验动物学报，2018,4:474－479.

[22] Emamian MH. Salt intake and blood pressure [J]. J Hypertens,2019,9:1530－1531.

引用本文

刘星星*,李丽丹,王斌鑫,吕锦彬. 高盐饮食对肾脏的影响 [J]. 国际临床研究杂志. 2022; 6; (7). 42 - 44.

文献评论

相关学者

相关机构