International Journal of Internal Medicine

Objective To explore the effect of dual plasma molecular adsorption system (DPMAS) + plasma exchange (PE) in the treatment of acute-on-chronic liver failure. Methods A total of 52 patients who were treated in our hospital from March 2020 to March 2022 were selected as the research subjects and randomly divided into groups. The control group was treated with plasma exchange, and the experimental group was treated with dual plasma molecular adsorption system on the basis of the former. The treatment efficiency, liver function and coagulation indexes of the two groups were compared, and the incidence of adverse reactions was also compared. Results The treatment efficiency of the experimental group was high, and the incidence of adverse reactions was low. There were significant differences in liver function indexes and coagulation indexes. Conclusion For the treat- ment of patients with acute-on-chronic liver failure, the combined application of dual plasma molecular adsorption system and plasma exchange has significant curative effect and good safety, which is worthy of promotion.

DPMAS; PE; Liver failure