注射鼠神经生长因子治疗慢性多发性周围神经病的疗效分析-国际内科前沿杂志-CSCIED科技核心评价数据库-手机版

注射鼠神经生长因子治疗慢性多发性周围神经病的疗效分析

Efficacy analysis of injection of mouse nerve growth factor in the treatment of chronic polyneuropathy

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DOI	10.12208/j. ijim.20220081
刊名	国际内科前沿杂志 International Journal of Internal Medicine
年，卷(期)	2022, 3(3)
作者	彭勃*,
作者单位	镇江市第一人民医院江苏镇江 ;
摘要	探讨慢性多发性周围神经病（CPP）患者注射鼠神经生长因子（mNGF）的疗效。方法共计纳入对象60例，均为CPP患者，双色球法分为两组，对照组用基础治疗，观察组则加mNGF注射治疗，对比疗效。结果治疗前两组MTT评分、SDR评分、VAS评分、生活质量评分比较无明显差异（P>0.05），治疗结束，观察组MTT评分、生活质量评分更高，而SDR评分、VAS评分更低，差异显著（P<0.05）；两组不良反应无明显差异（P>0.05）。结论 CPP予以mNGF注射治疗，可更好地改善患者的运动功能与感觉障碍，减轻患者的疼痛程度，促进患者生活质量提高，但不会明显增加不良反应，值得应用。
Abstract	Objective To investigate the efficacy of mouse nerve growth factor (mNGF) injection in patients with chronic polyneuropathy (CPP). Methods A total of 60 subjects, all of whom were CPP patients, were divided into two groups by the two-color ball method. The control group was treated with basic treatment, and the obser- vation group was treated with mNGF injection to compare the curative effects. Results There was no significant difference in MTT score, SDR score, VAS score and quality of life score between the two groups before treatment (P>0.05). After treatment, the MTT score and quality of life score of the observation group were higher, while the SDR score and VAS score were lower. The difference was significant (P<0.05); there was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion CPP with mNGF injection therapy can better improve the motor function and sensory disturbance of patients, reduce the pain degree of patients, and improve the quality of life of patients, but it will not significantly increase the adverse reactions, and it is worthy of application.
关键词	慢性多发性周围神经病；鼠神经生长因子；MTT评分；SDR评分；生活质量
KeyWord	Chronic polyneuropathy; Mouse nerve growth factor; MTT score; SDR score; Quality of life
基金项目
页码	49-52

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引用本文

彭勃*. 注射鼠神经生长因子治疗慢性多发性周围神经病的疗效分析 [J]. 国际内科前沿杂志. 2022; 3; (3). 49 - 52.

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