尼莫地平联合多奈哌齐治疗老年痴呆的临床效果

Clinical effect of nimodipine combined with donepezil in the treatment of senile dementia

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DOI 10.12208/j.ijcr.20220347
刊名
International Journal of Clinical Research
年,卷(期) 2022, 6(8)
作者
作者单位

南昌大学第四附属医院 江西南昌 ;

摘要
本文探究对老年痴呆患者实施尼莫地平+多奈哌齐进行治疗,其临床治疗效果。方法 此次选取我院在2019年12月-2022年5月期间进行治疗的98例老年痴呆患者作为研究对象,对比两组患者治疗效果和生活质量、词汇记忆评分以及不良反应发生情况。结果 联合用药治疗组治疗效果、生活质量、词汇记忆评分均优于多奈哌齐治疗组,P<0.05说明存在对比意义,而不良反应发生率无显著变化,P>0.05说明不存在对比意义。结论 对老年痴呆患者采取尼莫地平+多奈哌齐联合治疗,其治疗效果显著,说明该治疗方案具有较高的临床价值。
Abstract
Objective: To explore the clinical effect of nimodipine + donepezil in the treatment of senile dementia. Methods: 98 patients with Alzheimers disease who were treated in our hospital from December 2019 to may 2022 were selected as the study subjects to compare the treatment effect, quality of life and vocabulary memory score of the two groups of patients. Results: the treatment effect, quality of life and vocabulary memory score of the combined drug treatment group were better than that of the donepezil treatment group (P < 0.05), indicating that there was a comparative significance, while the incidence of adverse reactions had no significant change (P > 0.05), indicating that there was no comparative significance. Conclusion: the combination of nimodipine and donepezil is effective in the treatment of senile dementia, which indicates that the treatment scheme has high clinical value.
关键词
老年痴呆;尼莫地平;多奈哌齐;治疗效果
KeyWord
Senile Dementia; Nimodipine; Donepezil; Treatment Effect
基金项目
页码 13-15
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韩金晶,陈虹宇,杨宏武,周征成,楼小亮*. 尼莫地平联合多奈哌齐治疗老年痴呆的临床效果 [J]. 国际临床研究杂志. 2022; 6; (8). 13 - 15.

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