| Abstract |
Eosinophilic fasciitis refers to a connective tissue disease involving the deep fascia of the skin of limbs with scleroderma, also known as diffuse fasciitis of eosinophilic increase, Schulmans syndrome, etc. The main clinical manifestations are: acute onset, most patients have a history of overwork, and symmetrical skin swelling, swelling, pain, and stiffness, often in the limbs but involving other parts of the body. In general, patients often have joint pain, joint contracture and other symptoms[1-2]. Laboratory tests revealed peripheral eosinophilia and hypery-globulinemia. A classic feature of eosinophilic fasciitis is the groove sign, which is observed along the superficial veins and is most pronounced when the limb is elevated. Eosinophilic fasciitis is rare and causes delays in diagnosis and treatment. Identification of groove sign, a typical feature of eosinophilic fasciitis, is helpful for diagnosis[3-4]. In the diagnosis process, the main basis is: the history of overwork before the onset; Acute onset; Scleroderma-like skin lesions; Eosinophils in peripheral blood increased significantly. Skin histopathology showed deep fascial inflammation accompanied by eosinophil infiltration, while there were no significant changes in epidermis and dermis[5-6].
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