低频重复经颅磁刺激治疗对卒中后抑郁患者认知和日常生活能力的影响

Effects of low frequency repetitive transcranial magnetic stimulation on cognitive and daily life ability of patients with post stroke depression

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2016, 43(4)
作者
作者单位

中国人民解放军第254医院 ;

摘要
【摘要】探讨卒中后抑郁(PSD)患者采取低频重复经颅磁刺激(r-TMS)治疗的疗效。方法 选取120例于2014年5月至2015年5月期间我院接收的卒中抑郁患者伴轻度认知障碍患者,根据治疗方案的不同分为对照组与实验组,均给予盐酸氟西汀胶囊治疗,实验组加用低频重复经颅磁刺激治疗,观察两组疗效。结果 实验组抗抑郁疗效较对照组显著要优(P<0.05);在MoCA评分、MMSE评分、BI指数评分上治疗后,实验组均显著高于对照组(P<0.05);治疗期间仅有少数轻微头痛病例,未见其他严重不良反应。结论 低频r-TMS可显著改善PSD患者的认知功能、日常生活能力及抑郁症状,效果显著,具有较高的安全性,具有推广价值。
Abstract
[Abstract]Objective: To investigate the therapeutic effect of low frequency repetitive transcranial magnetic stimulation (r-TMS) in patients with post stroke depression (PSD).Methods: 120 cases of stroke depression patients with mild cognitive impairment in our hospital from May 2014 to May 2015 were selected. According to the different treatment methods, the patients were divided into control group and experimental group.All patients were treated with fluoxetine hydrochloride.The experimental group was treated with low frequency repetitive transcranial magnetic stimulation.The therapeutic effect of the two groups was observed.Results:The experimental group compared with the control group,significantly better than the control group (P<0.05); in the MoCA score, MMSE score, BI index score after treatment, the experimental group was significantly higher than the control group (P<0.05); only a few mild headache cases during the treatment, no other serious adverse reactions.Conclusion:Low frequency r-TMS can significantly improve the cognitive function, daily life ability and depressive symptoms of patients with PSD, the effect is significant, and it has high safety, and it has the value of popularization.
关键词
【关键词】卒中后抑郁;低频重复经颅磁刺激;日常生活能力;认知
KeyWord
[Key words]Post stroke depression;Low frequency repetitive transcranial magnetic stimulation; Daily life ability;Cognition
基金项目
页码 648-650
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邢效如*, 王魁恩,赵新春,孙志. 低频重复经颅磁刺激治疗对卒中后抑郁患者认知和日常生活能力的影响 [J]. 国际精神病学杂志. 2016; 43; (4). 648 - 650.

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