International Journal of Clinical Research

Objective To observe the efficacy of different treatment regimens for local recurrence of lung cancer. Methods The medical records of 70 patients admitted to our department from April 2024 to August 2025 were selected for analysis. The control group included 35 patients who received conventional radiotherapy, while the observation group consisted of 35 patients who underwent three-dimensional conformal radiotherapy (3-DCRT) + chemotherapy treatment. The treatment outcomes of the two groups were compared. Results In terms of overall effectiveness, the observation group vs. the control group was 85.71% vs. 51.43%, and the difference was statistically significant (P<0.05). During the treatment process, the incidence of toxic reactions in patients between the groups was similar, that is, the difference was not significant (P>0.05). Conclusion For patients with local recurrence of lung cancer, the treatment with 3-DCRT combined with chemotherapy is better at controlling the condition compared to simple radiotherapy, and it does not significantly increase the incidence of adverse reactions, with better long-term efficacy. It is worthy of promotion.

Local recurrence of lung cancer; Three-dimensional conformal radiotherapy; Chemotherapy; Short-term efficacy; Adverse reactions; Survival rate