International Journal of Clinical Research

Objective To analyze the effects of Zhenwu Decoction on the TCM syndrome score, left ventricular ejection fraction, and N-terminal pro-brain natriuretic peptide (NT-proBNP) in the treatment of chronic heart failure with Yang deficiency and water retention syndrome. Methods A total of 78 patients with chronic heart failure due to Yang deficiency and water retention syndrome who were received from October 2021 to October 2022 were included in the study. They were divided into the reference group (general treatment, n=39) and the study group (with Zhenwu Decoction added on the basis of general treatment, n=39) according to the treatment methods. The cardiac function indicators, TCM syndrome scores, activities of daily living and adverse reactions before and after treatment were compared between the two groups. Results After treatment, the TCM syndrome score and NT-proBNP of the study group were lower than those of the reference group, while the left ventricular ejection fraction and activities of daily living score were higher than those of the reference group (P < 0.05). The occurrence rate of adverse reactions in the study group was not statistically significant compared with that in the reference group (P > 0.05). Conclusion For patients with chronic heart failure due to Yang deficiency and water retention syndrome, the implementation of Zhenwu Decoction treatment can improve cardiac function, alleviate clinical symptoms of traditional Chinese medicine, enhance the ability to perform daily activities, and has few adverse reactions.

Syndrome of yang deficiency with water flooding in chronic heart failure; Zhenwu Decoction; Cardiac function