International Journal of Clinical Research

Objective To analyze and explore the effects of acupuncture combined with acupoint application on clinical symptoms and inflammatory factor levels in patients with non-alcoholic fatty liver disease (NAFLD), aiming to provide theoretical and practical references for clinical research. Methods The study was conducted through comparative analysis, with the period from September 2023 to September 2024 designated as the study duration. A total of 82 NAFLD patients were enrolled as the study subjects, and the patients were assigned to groups using a two-color ball grouping method, with 41 cases in each group (n=41). The groups were named the reference group and the study group, respectively. Different treatment intervention plans were implemented: the reference group received conventional treatment, while the study group received conventional treatment combined with acupuncture and acupoint application. Clinical data and related information were collected and analyzed, with clinical symptom scores, liver function indicators, lipid levels, inflammatory factors, and quality of life scores used as observation indicators to compare the effects and differences under different intervention strategies. Results Statistical analysis revealed that the study group demonstrated significantly better overall intervention outcomes, with all indicators showing superior values compared to the reference group (P-value <0.05), warranting further discussion. Conclusion For patients with non-alcoholic fatty liver disease, the combined intervention model (conventional treatment + acupuncture combined with acupoint application) is recommended as the preferred clinical treatment option. This approach not only effectively improves clinical symptoms and reduces inflammatory factor levels but also significantly promotes liver function recovery, demonstrating significant clinical value and worthy of promotion.

Acupuncture; Acupoint application; Non-alcoholic fatty liver disease (NAFLD); Clinical symptoms; Inflammatory cytokine levels; Influence