International Journal of Clinical Research

Objective To observe the effect of modified Taohe Chengqi Decoction combined with low-dose mannitol on the treatment of acute cerebral edema in patients with hypertensive intracerebral hemorrhage, and its impact on the levels of C-reactive protein and procalcitonin in patients. Methods A prospective study was conducted on 80 patients with acute phase cerebral edema of hypertensive intracerebral hemorrhage from June 2024 to December 2025. The patients were randomly divided into two groups using a digital table. The control group (40 cases) received conventional treatment plus low-dose mannitol treatment, while the observation group (40 cases) received modified Taohe Chengqi Decoction on the basis of treatment in the control group. Observe the absorption of cerebral edema, improvement of neurological function, C-reactive protein, and procalcitonin levels in two groups of patients. Results The absorption rate of cerebral edema in the observation group was higher than that in the control group, (P<0.05). The NIHSS score in the observation group was lower than that in the control group after treatment, and the GCS score in the observation group was higher than that in the control group after treatment, (P<0.05). The levels of C-reactive protein and procalcitonin in the observation group were lower than those in the control group after treatment, (P<0.05). Conclusion In the treatment of acute cerebral edema in patients with hypertensive intracerebral hemorrhage, the combination of modified Taohe Chengqi decoction and low-dose mannitol can help improve the absorption rate of cerebral edema, promote the recovery of damaged nerve function, reduce the levels of C-reactive protein and procalcitonin, and facilitate the recovery of patients.

Modified taohe chengqi decoction; Low dose mannitol; Hypertensive intracerebral hemorrhage; Acute phase cerebral edema; C-reactive protein; Procalcitonin