宁夏地区儿童特异性IgE抗体检测与过敏性疾病的相关性研究-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

宁夏地区儿童特异性IgE抗体检测与过敏性疾病的相关性研究

Study on the correlation between specific IgE antibody testing in children in the Ningxia region and allergic diseases

ES评分 0 浏览量：39 下载量：0

DOI	10.12208/j.ijcr.20260173
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2026, 10(4)
作者	丁吉梅, 段菊玲, 马学, 申雪茹, 杨齐, 张玲,
作者单位	北京大学第一医院宁夏妇女儿童医院宁夏银川;
摘要	目的探讨宁夏地区儿童特异性IgE（sIgE）抗体阳性分布特征及其与过敏性疾病的相关性。方法选取2025年1月-2025年12月就诊的疑似过敏性疾病患儿862例为研究对象，采用免疫印迹法检测总IgE及20种过敏原sIgE抗体，统计不同变量下的阳性率并分析关联性。结果患儿sIgE抗体总阳性率为68.45%，过敏性鼻炎阳性率最高，吸入性过敏原阳性率高于食物性，10~14岁年龄段阳性率最高，性别差异无统计学意义；sIgE抗体阳性与疾病发生及严重程度均呈正相关。结论宁夏地区儿童过敏性疾病与sIgE抗体阳性密切相关，该检测对疾病诊疗与防控具有重要指导价值。
Abstract	Objective To investigate the distribution characteristics of specific IgE (sIgE) antibodies in children in Ningxia region and their correlation with allergic diseases. Methods A total of 862 children with suspected allergic diseases who visited the hospital from January 2025 to December 2025 were selected as the research subjects. Total IgE and 20 types of allergen sIgE antibodies were detected by immunoblotting. The positive rates under different variables were statistically analyzed and their correlations were investigated. Results The total positive rate of sIgE antibodies in children was 68.45%. The positive rate of allergic rhinitis was the highest, and the positive rate of inhalant allergens was higher than that of food allergens. The positive rate was the highest in the 10-14 age group, and there was no statistical significance in gender differences. The positive sIgE antibodies were positively correlated with the occurrence and severity of the disease. Conclusion Allergic diseases in children in Ningxia region are closely related to positive sIgE antibodies. This detection has important guiding value for disease diagnosis, treatment and prevention.
关键词	儿童；特异性IgE抗体；过敏性疾病；相关性；宁夏地区；过敏原谱
KeyWord	Children; Specific IgE antibodies; Allergic diseases; Correlation; Ningxia region; Allergen spectrum
基金项目
页码	13-16

参考文献
相关文献

[1] 晋晶,谭婧,曹喜俊,等. 广州地区湿热气候下儿童鼻鼽患者IgE抗体与过敏原相关性研究
[J]. 山西中医药大学学报,2025,26(9):983-987,992.

[2] 陈雯,李玮泽,彭霞. 1 701例儿童血清过敏原特异性IgE检测结果分析
[J]. 检验医学与临床,2024,21(2):145-150.

[3] 王鹏立,徐丽娜,蒋吴君,等. 2018-2021年苏州地区儿童过敏原特异性IgE调查研究
[J]. 临床儿科杂志,2024, 42(3):198-203,217.

[4] 李汉华,吴亚洲,靳艺歆,等. 2020—2024年上海市某儿童医院常见过敏原致敏特征及变化趋势分析
[J]. 中华预防医学杂志,2025,59(6):844-856.

[5] 郭丽,那飞扬,梁譞,等. 兰州某医院1976例过敏性疾病儿童过敏原特异性IgE结果分析
[J]. 甘肃医药,2025, 44(10):889-893.

[6] 陈雪耐,肖建军,卢凌亚,等. 宁波市前湾新区2610例过敏性疾病患儿过敏原特异性IgE分布特征研究
[J]. 现代生物医学进展,2025,25(14):2279-2287.

[7] 李娟,胡广成,陈欢欢,等. 400例过敏性疾病患儿血清特异性IgE检测过敏原结果构成研究
[J]. 罕少疾病杂志,2024,31(9):142-144.

[8] 郭改丽. 北京某医院常见呼吸道过敏性疾病儿童过敏原特异性IgE检测的临床价值研究
[J]. 中国医学创新,2025,22(29):156-162.

引用本文

丁吉梅, 段菊玲, 马学, 申雪茹, 杨齐, 张玲. 宁夏地区儿童特异性IgE抗体检测与过敏性疾病的相关性研究 [J]. 国际临床研究杂志. 2026; 10; (4). 13 - 16.

文献评论

相关学者

相关机构