| 摘要 |
分析500例长期服用抗精神病药患者的腹部超声检查结果, 为抗精神病药物的合理运用提供参考。方法 选择2008年5月~2014年5月我院收治的500例长期服用抗精神病药患者行腹部 B超检查,比较不同年龄、服药时间及性别的精神病患者的腹部 B超检查结果。结果 273例患者月复部 B超检查出现异常, 异常率54.6%, 其中脾肿大52例, 单纯脂肪肝95例, 胆表结石46例, ·t更性胆愛炎41例,肝脏弥漫性改变32例,其他病变7例;病程及服药时间≥6 年组腹部 B超异常率高于病程及服药时间<6年组,差异有统计学意义(P<0.05) ;年龄≥60岁纽渡部 B超异常率高于年龄<60岁组,差异有统计学意义(P<0.05) ;不同性别患者月复部 B超异常率差异无统计学意义 (P>0. 05) 。 结论 长期服用抗精神病药的精神病患者, 发生脾肿大、 单纯月言肪肝、 脂肪肝合并胆愛结石、 脂月方肝合并月旦愛息肉等异常的比例较大, 病程及服药时间越长、年龄越大, 发生腹部超声异常的比例越高, 但与性别无关 。
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| Abstract |
〇bjective To analyse the abdominal ultrasound results of 500 cases of patients with long-term use of antipsychotics, in order to provide a re」ference for reasonable use of antipsychotics. Methods From May 2008 to May2014 in our hospita1, 500 cases of patients with1ong-term use of antipsychotics were accepted abdomi- nal ultrasound examination, and the results of type-B ultrasonic were analyzed. Results The abnormal rate of ab- dominal ultrasound was54. 6% (273/500) , including52 cases of splenomegaly, 95 cases of fattyliver disease, 46 cases of cholecystolithiasis, 41 cases of chronic cholecystitis, 32 cases of diffuseliver changes, and7 cases of other lesions. The group of patienLs with6 or more years course had higher abnormal raLs Lhan that of the group o」f paLients withless than6 years course, the difference was statistica11y significant(P<0.05); The group of patients more than60 years old had higher abnormal rate than that of the group of patientsless than60 years old, the difference was statistically significant(1)<0.05) ; There were no statistical significance difference in abdomina1 ultrasound ab- normality rate between different gender patients (P>0. 05). Conclusion The patients withlong-term use of antip- sychotic medecines have high rate of splenomegaly, simple fattyliver, fattyliver merger gallstones, fattyliver, gall- bladder polyp and other abmormity, the course of the disease, treatment time and age were the risk factors of abnor- mal results of abdominal ulLrasound.
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