International Journal of Clinical Research

Objective To investigate the effects of Anlna Massage Cream and Chest Essence Mask on a rat model of mammary gland hyperplasia. Methods The mammary gland hyperplasia model was established in female rats. Anlna Massage Cream was applied daily, or the Chest Essence Mask was patch-applied, for 7 or 15 days. Thereafter, the nipple height and diameter were measured. The rats were then anesthetized for blood collection and euthanized. The uterus was removed and weighed to calculate the uterine index. Serum levels of estradiol (E2), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and progesterone (P) were measured using ELISA. Results The model group showed significantly enlarged and protruding nipples, increased uterine index, significantly higher serum levels of E2, LH, and FSH compared to the blank group, and significantly lower serum P levels, indicating successful modeling. Both the Anlna Massage Cream group and the Essence Mask group significantly reduced nipple height and diameter, decreased the uterine index, lowered serum E2, LH, and FSH levels, and increased serum P levels in the model rats. Conclusion Anlna Massage Cream and Essence Mask can improve estrogen levels and alleviate mammary gland hyperplasia in rats.

Anlna Massage Cream; Anlna Chest Essence Mask; Hyperplasia of mammary glands; Uterine Index; E2; P; LH; FSH