International Journal of Clinical Research

Objective To explore the value of tumor necrosis factor -α (TNF-α), interleukin-6 (IL-6), and interleukin-17A (IL-17A) in the clinical diagnosis of ovarian malignant tumor diseases. Methods A total of 90 patients with ovarian malignant tumors who were treated in the gynecology department of Pizhou People's Hospital from January 2023 to December 2024 were selected as the research subjects of the observation group, and 90 healthy women who underwent physical examinations in the same hospital during the same period were selected as the research subjects of the control group. TNF-α, IL-6 and IL-17A were examined, and the examination results of the two groups of research subjects were compared. Results The three indicators of the observation group were all higher than those of the control group (p < 0.05). Among the patients with ovarian malignant tumors in the observation group, with the increase of disease stage, the three indicators showed an increasing trend, among which the three indicators of patients in stage IV were the highest (p < 0.05). Conclusion The detection of TNF-α, IL-6 and IL-17A indicators can serve as a basis for the clinical diagnosis of ovarian malignant tumor diseases. Meanwhile, the numerical range can assist in determining the disease stage, which is worth learning from.

Tumor necrosis factor alpha; Interleukin-6; Interleukin-17A; Testing