International Journal of Clinical Research

Objective Exploring the clinical application effect of nasal high flow oxygen therapy in reducing hypoxemia during painless gastroscopy in patients with coronary heart disease. Methods Sixty patients with coronary heart disease who underwent painless gastroscopy in our hospital from May 2023 to May 2025 were randomly divided into a high flow group and a conventional group, with 30 patients in each group, using a random number table method. During gastroscopy, the routine group received routine nasal cannula oxygen therapy, while the high flow group received nasal high flow oxygen therapy. The changes in blood oxygen saturation (SpO₂) between the two groups were observed, and the incidence of hypoxemia and interruption of examination were compared between the two groups. Results The SpO2 levels in the high flow group were significantly higher than those in the conventional group at 5 minutes after anesthesia, 10 minutes after anesthesia, 5 minutes after completion of gastroscopy, and 5 minutes after surgery (P<0.05). The incidence of intraoperative hypoxemia in the high flow group (0) was significantly lower than that in the conventional group (16.67%) (P<0.05). The interruption rate of the high traffic group (0) was not significantly different from that of the conventional group (3.33%) (P>0.05). Conclusion The use of high flow oxygen therapy through the nose during painless gastroscopy in patients with coronary heart disease can better maintain SpO2 levels and effectively reduce the incidence of hypoxemia, which helps to improve the safety of painless gastroscopy in such patients.

Nasal high flow oxygen therapy; Coronary heart disease; Painless gastroscopy examination; Hypoxemia; Interrupt check