International Journal of Clinical Research

Objective To explore the adverse reactions to DTP (diphtheria, tetanus, pertussis) vaccination and specific prevention and treatment strategies. Methods This study investigated 130 children who received DTP vaccination at the Center for Disease Control and Prevention from October 2022 to January 2025 through a grouped research design. According to a random number table method, the children were divided into a reference group (n=65) and a study group (n=65), forming two intervention groups. The reference group received routine management intervention, while the study group received risk management vaccination intervention. The total incidence of adverse reactions and overall family satisfaction of children in both groups were observed and compared. Results The total incidence of adverse reactions in the study group was significantly lower compared to the reference group (P<0.05). The overall family satisfaction in the study group was significantly higher than that in the reference group (P<0.05). Conclusion Children receiving DTP vaccination may experience certain vaccination reactions. In this situation, reasonably selecting a risk management vaccination approach and providing corresponding interventions can help reduce the incidence of adverse reactions and achieve higher family satisfaction.

DPT vaccine; Immunization; Prevention and control strategies; Adverse reactions; Family satisfaction