International Journal of Clinical Research

Objective To explore the clinical characteristics and nursing intervention measures of skin necrosis caused by extravasation of hypertonic 50% glucose injection in hemodialysis patients with diabetes. Methods The clinical data of a maintenance hemodialysis patient with diabetes who suffered from left upper limb swelling, blister formation and skin necrosis due to 50% glucose injection extravasation were retrospectively analyzed, and the comprehensive nursing measures under multidisciplinary cooperation were summarized. Results After stopping infusion, local debridement, and application of growth factor gel combined with hydrocolloid dressing, the wound healed completely within 9 days, limb function returned to normal, no sequelae occurred, and the wound healed well after 3 months of follow-up. Conclusion Hemodialysis patients with diabetes have poor vascular conditions and weak repair ability, and the risk of extravasation is very high when hypertonic drugs such as 50% glucose are infused, so dialysis pipelines should be preferred for fluid replacement; Timely adoption of tiered wound care and multidimensional comprehensive intervention after extravasation can effectively promote wound healing and improve patient prognosis.

Hemodialysis; Diabetes; Extravasation; Skin necrosis