International Journal of Clinical Research

Objective Investigate the clinical therapeutic effect of Guipi Decoction on elderly patients with depression characterized by deficiency of both the heart and spleen. Methods This study selected 90 elderly patients with heart and spleen deficiency type depression admitted to our hospital from 2022 to 2024 as research subjects. They were randomly assigned using a random number table to a control group (45 cases, receiving conventional Western medical treatment) and a study group (45 cases, receiving Guipi Decoction treatment). The treatment effects of the two groups of patients were compared and analyzed. Results Compared with the control group, patients in the study group had significantly lower scores in traditional Chinese medicine syndrome points, Hamilton Depression Rating Scale and Pittsburgh Sleep Quality Index, while their quality of life scores were higher, with all intergroup differences being statistically significant (P<0.05). Conclusion Using Guipi Decoction to treat elderly patients with depression characterized by both heart and spleen deficiency can effectively alleviate various symptoms, ease their depressive mood, and improve their sleep quality and overall quality of life.

Guipi decoction; Heart-spleen deficiency type; Elderly; Depression