International Journal of Clinical Research

Objective To investigate the effects of three anesthesia regimens—total intravenous anesthesia combined with dexmedetomidine, total intravenous anesthesia combined with low-MAC sevoflurane, and total intravenous anesthesia—on somatosensory evoked potentials (SEP) and motor evoked potentials (MEP) during scoliosis correction surgery. Methods A total of 249 patients scheduled for scoliosis correction surgery from March 2024 to March 2025 were randomly divided into group A (n=83, total intravenous anesthesia combined with dexmedetomidine), group B (n=83, total intravenous anesthesia combined with low-MAC sevoflurane), and group C (n=83, total intravenous anesthesia). SEP latency, MEP amplitude, and the incidence of abnormal indicators were monitored preoperatively, intraoperatively, and postoperatively. Results The intraoperative N20 latency in the upper limbs (18.25±1.36 ms) and P40 latency in the lower limbs (42.18±2.57 ms) in group A were significantly shorter than those in groups B and C (P<0.05). The mean amplitude of MEP in group A (286.45±32.18 μV) was higher than that in groups B and C (P<0.05). The abnormality rate in group A was 3.61%, lower than that in group B (13.25%) and group C (10.84%) (P<0.05). Conclusion General anesthesia combined with dexmedetomidine can stabilize SEP and MEP indices during scoliosis correction surgery, reduce the abnormality rate, and facilitate neurological function monitoring.

Scoliosis correction surgery; Anesthesia method; Somatosensory evoked potentials; Motor evoked potentials; Neurophysiological monitoring