即时检验(PCT)在结核病快速诊断中的应用效果及质量控制

Application effect and quality control of point-of-care testing (PCT) in the rapid diagnosis of tuberculosis

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DOI 10.12208/j.ijcr.20260123
刊名
International Journal of Clinical Research
年,卷(期) 2026, 10(3)
作者
作者单位

阿克苏地区第三人民医院(阿克苏地区传染病医院) 新疆阿克苏;

摘要
目的 探究即时检验(PCT)在结核病快速诊断中的应用效果以及质量控制。方法 选择2024年8月份至2025年8月份于我院接受检测的120例患者进行研究,依据最终诊断分成对照组和实验组,每组60例,对照组为非结核人群;实验组结核病组,所有人员均提供即时检验、化学发光法进行检测,判断诊断效能;对比PCT水平,判断相关性。结果 出现结核的患者PCT水平低于非结核人群(P<0.05),将PCT<0.25 ng/mL完成辅助结核病检测时,阳性患者的PCT水与痰涂片菌量分级为弱正相关。结论 POCT-PCT检测快速且便捷,在结核病诊断当中具有较高的价值,但PCT水平低作为结核病的相对特征,但无法作为确诊或者排除的独立指标,建立系统化的质量控制,可以保证检验结果的准确性,为临床决策提供依据。
Abstract
Objective To explore the application effect and quality control of point-of-care testing (PCT) in the rapid diagnosis of tuberculosis. Methods 120 patients who were tested in our hospital from August 2024 to August 2025 were selected for the study. They were divided into the control group and the experimental group according to the final diagnosis, with 60 cases in each group. The control group consisted of non-tuberculosis patients; the experimental group was the tuberculosis group. All individuals provided point-of-care testing and chemiluminescence method for detection to determine the diagnostic efficacy; compare the PCT levels and determine the correlation. Results The PCT levels of patients with tuberculosis were lower than those of non-tuberculosis patients, p < 0.05. When PCT < 0.25 ng/mL was used as an auxiliary test for tuberculosis diagnosis, the PCT levels of positive patients were positively correlated with the grade of acid-fast staining (smear microscopy) in sputum smear. Conclusion POCT-PCT testing is rapid and convenient, and has high value in the diagnosis of tuberculosis. However, a low PCT level is a relative characteristic of tuberculosis, but cannot be an independent indicator for diagnosis or exclusion. Establishing a systematic quality control can ensure the accuracy of the test results and provide a basis for clinical decision-making.
关键词
即时检验;结核病快速诊断;应用效果;质量控制
KeyWord
Point-of-care testing; Rapid diagnosis of tuberculosis; Application effect; Quality control
基金项目
页码 30-32
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梅航川. 即时检验(PCT)在结核病快速诊断中的应用效果及质量控制 [J]. 国际临床研究杂志. 2026; 10; (3). 30 - 32.

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