International Journal of Clinical Research

Objective To investigate the prognostic value of ultrasonic shear wave elastography (SWE) in patients with liver fibrosis and analyze the correlation between its detection parameters and clinical recovery, laboratory tests, and quality of life. Methods A total of 60 patients with chronic hepatitis B-related liver fibrosis from January 2025 to January 2026 were enrolled at Qiqihar First Hospital and randomly divided into an observation group (n=30) and a control group (n=30). A retrospective analysis was conducted using 30 healthy individuals as a blank control group from January 2023 to December 2024. The observation group underwent 2D-SWE combined with conventional ultrasound examination, while the other two groups received only conventional ultrasound examination. The prognostic value of the three groups was compared. Results In the observation group, the Young's modulus and ElastPQ values gradually increased, while the total score and dimensions of the CLDQ score gradually decreased. The severity of abnormal liver function indicators worsened (P<0.05). Correlation analysis revealed that the Young's modulus and ElastPQ values were significantly negatively correlated with the total CLDQ score (r=-0.682, -0.635, P<0.05), and the AST/PLT ratio and FIB-4 index were negatively correlated with the total CLDQ score (r=-0.571, -0.528, P<0.05). Conclusion Ultrasound shear wave elastography can be used to assess the degree of liver fibrosis and prognosis, and its detection index is related to the recovery and quality of life of patients, which provides a basis for noninvasive diagnosis and prognosis monitoring.

Ultrasonic shear wave elastography; Liver fibrosis; Prognosis; Correlation Analysis