International Journal of Clinical Research

Objective To discuss and study the application effect of Xiliaotuo combined with different injection methods in improving the adverse reactions of azacitidine subcutaneous injection. Methods Sixty patients who received azacitidine in our hospital from January 2025 to December 2025 were selected for the study. They were randomly divided into the control group and the experimental group by the random number table method, with 30 cases in each group. The control group received routine injections, while the experimental group received regional rotation injections combined with Xiliaotuo application after injection. The pain levels of the two groups were compared. Incidence of adverse reactions. Results After providing different intervention measures to the two groups of patients, the pain degree in the experimental group was lower than that in the control group, P<0.05. In contrast, the incidence of adverse reactions in the experimental group was even lower, p<0.05. Conclusion For patients who receive subcutaneous injection of azacitidine, providing rotational area subcutaneous injection combined with application of Xiliaotuo after injection can enhance the comfort of patients and reduce the occurrence of complications, which is worthy of promotion.

Xiliaotuo; Different injection methods; Azacitidine; Subcutaneous injection; Adverse reactions