合并抑郁对PCI术后心肌损伤标志物及心率变异性的影响
Effect of Combined Depression on Post-PCI Myocardial Injury Markers and Heart Rate Variability
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| DOI |
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| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2026, 53(1) |
| 作者 |
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| 作者单位 |
河南省直属机关第一门诊部
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| 摘要 |
摘要：目的 探讨合并抑郁对经皮冠状动脉介入术（percutaneous coronary intervention，PCI）后心肌损伤标志物及心率变异性的影响。方法 选择2023年3月-2025年5月103例冠心病患者，评估抑郁自评量表并分为抑郁组与无抑郁组，PCI术后检测心肌损伤标志物[心肌肌钙蛋白I（cardiac troponin，cTnI）、肌酸激酶同工酶(creatine kinase isoenzyme, CK-MB)]、心率变异性 (SDNN、SDANN、LF/HF)。结果 103例冠心病患者38例合并抑郁情绪；抑郁组PCI术后血清cTnI、CK-MB均显著高于无抑郁组，（P<0.05）；抑郁组PCI术后SDNN、SDANN低于无抑郁组，LF/HF高于无抑郁组，（P<0.05）。结论 冠心病患者容易出现抑郁情绪，而且，合并抑郁情绪术后心肌损伤标志物水平更高，心率变异性更差。
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| Abstract |
[Abstract] Objective To investigate the impact of comorbid depression on myocardial injury markers and heart rate variability following percutaneous coronary intervention (PCI). Methods A total of 103 patients with coronary heart disease were enrolled between March 2023 and May 2025. Participants were assessed using the Self-Rating Depression Scale and categorized into depressed and non-depressed groups. Post-PCI monitoring of myocardial injury markers [cardiac troponin I (cTnI), creatine kinase isoenzyme (CK-MB)] and heart rate variability (SDNN, SDANN, LF/HF). Results Among 103 patients with coronary heart disease, 38 also experienced depressive symptoms. Post-PCI serum cTnI and CK-MB levels were significantly higher in the depressed group than in the non-depressed group (P<0.05). Post-PCI SDNN and SDANN were lower in the depressed group, while LF/HF was higher compared to the non-depressed group (P<0.05). Conclusion Patients with coronary heart disease are prone to depressive symptoms. Furthermore, those with comorbid depression exhibit higher levels of postoperative myocardial injury markers and poorer heart rate variability.
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| 关键词 |
关键词：抑郁；冠心病；经皮冠状动脉介入术；心肌损伤标志物；心率变异性
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| KeyWord |
Key words Depression; Coronary Heart Disease; Percutaneous Coronary Intervention; Cardiac Injury Markers; Heart Rate Variability
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| 基金项目 |
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| 页码 |
199-201 |
郭兴.
合并抑郁对PCI术后心肌损伤标志物及心率变异性的影响 [J].
国际精神病学杂志.
2026; 53; (1).
199 - 201.