Journal of International Psychiatry

【Abstract】Objective To observe the depression status in children with congenital hypothyroidism (CH) and analyze its influencing factors. Methods The clinical data of 112 children with CH who visited our hospital from January 2022 to December 2023 were retrospectively analyzed. The depression status of the children was assessed using the Depression Self-Rating Scale for Children (DSRSC). The 112 children were divided into a depressed group (30 cases) and a non-depressed group (82 cases). The Self-Rating Scale for Depressive Disorder in Childhood (DSRSC) was used to assess children's depression. Clinical data of the two groups were collected and compared. Multivariate Logistic regression analysis was used to explore the influencing factors of depression in children with CH. Results The proportion of children adopting encouraging parenting styles, free triiodothyronine (FT3), free thyroid hormone (FT4), subjective support scores, objective support scores, and support utilization scores in the depressed group were significantly lower than those in the non-depressed group. The Achenbach Child Behavior Checklist (CBCL) scores in the depressed group were significantly higher than those in the non-depressed group (P < 0.05). Multivariate Logistic regression analysis showed that parenting style, FT3, FT4, CBCL score, subjective support score, objective support score and support utilization score were the influencing factors for depression in children with CH (P < 0.05). Conclusions The influencing factors of mental health of children with CH include parenting style, FT3, FT4, CBCL score and social support score. Clinical attention and intervention can be paid to these factors.

【Key words】Congenital hypothyroidism; Children; Depression; Influencing factors