Journal of Chemistry and Chemical Research

Continuous flow reactors bring about process innovation API synthesis with unique advantages. Its efficient mass and heat transfer characteristics significantly enhance the efficiency and selectivity of reactions, precise control of reaction conditions enhances the stability and safety of the process and the microchannel structure also provides a reliable way to achieve dangerous reactions. The combination of continuous flow reactors and online analysis technology has realized real-time monitoring and optimization, and continuous production mode is more in line with the concept of green chemistry and sustainable development. By analyzing the key elements of intensified process of continuous flow reactors in API synthesis, the direction potential of their in-depth application in this field are explored, and theoretical and practical references are provided for promoting the technological upgrading of API synthesis.

Continuous flow; API synthesis; Process intensification; Microchannel; Green chemistry