精神分裂症恢复期复发影响因素研究

Analysis on Risk Factor of Relapse of Schizophrenia

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(3)
作者
作者单位

石家庄市第八医院精神五科 ;
河北医科大学附属第二医院 内分泌科 ;
石家庄市第八医院 精神五科 ;

摘要
摘 要 了解精神分裂症复发的相关影响因素。方法 以2012年~2013年河北省石家庄市第八医院诊断为精神分裂症的192名患者为对象,随访3年,了解患者恢复期的复发情况,运用自制的调查问卷收集患者基础资料、临床资料,采用二分类Logistic回归分析精神分裂症复发影响因素。结果 192例精神分裂症患者3年内复发93例,复发率48.44%,多因素分析发现男性,家庭支持一般、差,未婚、离婚,偏执型患者,病程<1年,有精神病家族史服药不依从是精神分裂症复发的危险因素。尤其是有精神病家族史(OR=4.837,95%CI:2.514~7.326),服药不依从(OR=3.159,95%CI:1.745~4.467)是精神分裂症复发的主要危险因素。结论 精神分裂症患者复发受到遗传、服药依从性、家庭环境、疾病的病程、类型等多种因素的影响,建立社区为基础的精神分裂症患者个案管理,规范药物治疗,加强家庭支持是降低精神分裂症患者复发的有力措施。
Abstract
Abstract Objective: To know the risk factors of relapse of schizophrenia. Methods: 192 schizophrenia patients which the basic information and the clinical relevant information were collected by questionnaire were enrolled to carry out the risk factors analysis. The risk factors were analyzed by logistic regression model. Results: 93 patients relapsed schizophrenia in 3 years and the rate of relapse was 48.44%. The logistic regression analysis shown sexy, family support, marital status, type and duration of illness, family history of Schizophrenia, treatment compliance were factors of relapse of schizophrenia, especially family history of Schizophrenia(OR=4.837, 95%CI: 2.514~7.326) and treatment compliance(OR=3.159, 95%CI: 1.745~4.467)were the most main risk factors. Conclusion: There were many factors to influence the relapse of schizophrenia. The results suggest community follow up management for schizophrenia, strengthen treatment compliance and family support were useful for preventing relapse of schizophrenia.
关键词
关键词 精神分裂症;复发;影响因素
KeyWord
Key words Schizophrenia; Relapse; Factors
基金项目
页码 411-413
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张红梅*,赵占胜,孙志刚,李素水,肖庆国,宋丽华. 精神分裂症恢复期复发影响因素研究 [J]. 国际精神病学杂志. 2017; 44; (3). 411 - 413.

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