Journal of International Psychiatry

[Abstract] Objective: To investigate the preventive effect of butylphthalamide and sodium chloride injection on cerebral infarction patients with cerebral infarction. Methods: 60 patients with acute cerebral infarction were randomly divided into study group and control group (n = 30). The patients in the two groups were treated with routine therapy. The study group (NIHSS) was used to evaluate the neurological deficits of the two groups before and after treatment, and the patients were treated with Hamilton sodium phosphate, and the patients were treated with butylphthalamide and sodium chloride injection. The patients were treated with Hamilton Depression Scale (HAMD) was used to evaluate the performance of depression in both groups before and after treatment. Results: There was no significant difference in NIHSS score between the two groups before treatment (P> 0.05). The NIHSS score of the two groups was significantly lower than that of the control group (P <0.05), the difference was statistically significant (P < 0.05). There was no significant difference in HAMD score between the two groups before treatment (P> 0.05). The HAMD score of the study group was significantly lower than that of the control group (P <0.05). Conclusion: The treatment of cerebral infarction in patients with cerebral infarction can effectively improve the neurological deficits of patients, and can prevent the occurrence of depression after cerebral infarction. It is worthy to be popularized and applied in clinical practice.

[Key words] Cerebral infarction; Post-cerebral infarction depression; Butylphthalide sodium chloride injection; Neurological deficit