加味泻黄散治疗脾胃湿热型口臭的疗效观察-国际中医药研究-CSCIED科技核心评价数据库-手机版

加味泻黄散治疗脾胃湿热型口臭的疗效观察

Modified Xiehuang San spleen-stomach damp-heat type halitosis clinical observation on the therapeutic effect

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DOI	10.12208/j.ircm.20250043
刊名	国际中医药研究 International Research in Chinese Medicine
年，卷(期)	2025, 5(4)
作者	林祖英, 宋千慧, 滕荣阁, 赵春芳,
作者单位	广西中医药大学赛恩斯新医药学院广西南宁
摘要	目的探讨加味泻黄散治疗脾胃湿热型口臭的临床疗效及对患者体质的改善作用。方法从广西中医药大学赛恩斯新医药学院中选取符合诊断标准的脾胃湿热型口臭患者54例，按照随机信封法分成治疗组和对照组各27例。对照组采用生活管理联合泻黄散治疗，治疗组采用生活管理联合加味泻黄散治疗，两组均以4天为1疗程，连续治疗2个疗程（共8天），并于治疗结束后24小时内进行疗效评估。通过Rosenberg分级标准、口臭检测仪检测及《中医体质辨识表》，对比两组患者治疗前后口臭症状及脾胃湿热体质改善情况。结果治疗后，治疗组临床痊愈率、显效率及总有效率均显著高于对照组（P<0.05）；治疗后，两组湿热质转化分均明显低于治疗前（P<0.05），治疗组改善效果明显优于对照组（P<0.05）。结论在为期8天的治疗中，加味泻黄散能有效改善脾胃湿热型口臭患者的临床症状，调节湿热体质，其近期疗效优于经典泻黄散方，且未增加不良反应，值得临床推广。
Abstract	Objective To investigate the clinical efficacy of Modified Xiehuang San in the treatment of halitosis of Spleen-Stomach Damp-Heat type and its effect on improving patients’ physical constitution. Methods Fifty-four patients with halitosis of Spleen-Stomach Damp-Heat type who met the diagnostic criteria were selected from Saien Sino-New Medical College, Guangxi University of Chinese Medicine. They were randomly divided into treatment group and control group by random envelope method, with 27 cases in each group. The control group was treated with lifestyle management combined with Xiehuang San, while the treatment group received lifestyle management combined with Modified Xiehuang San. Both groups were treated for 2 consecutive courses (8 days in total), with 4 days as one course. The curative effect was evaluated within 24 hours after treatment. The halitosis symptoms and improvement of Spleen-Stomach Damp-Heat constitution before and after treatment were compared between the two groups by Rosenberg grading scale, halitosis detector and Constitution Identification Scale of Traditional Chinese Medicine. Results After treatment, the clinical cure rate, markedly effective rate and total effective rate in the treatment group were significantly higher than those in the control group (P<0.05). After treatment, the Damp-Heat constitution scores of both groups were significantly lower than those before treatment (P<0.05), and the improvement in the treatment group was significantly better than that in the control group (P<0.05). Conclusion In the 8-day treatment, Modified Xiehuang San can effectively improve the clinical symptoms of patients with halitosis of Spleen-Stomach Damp-Heat type and regulate Damp-Heat constitution. Its short-term efficacy is superior to the classic Xiehuang San prescription without increasing adverse reactions, which is worthy of clinical promotion.
关键词	加味泻黄散；脾胃湿热型；口臭；临床疗效；体质调节
KeyWord	Modified Xiehuang San; Spleen-stomach damp-heat type; Halitosis; Clinical efficacy; Constitution regulation
基金项目
页码	53-57

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引用本文

林祖英, 宋千慧, 滕荣阁, 赵春芳. 加味泻黄散治疗脾胃湿热型口臭的疗效观察 [J]. 国际中医药研究. 2025; 5; (4). 53 - 57.

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