International Journal of Clinical Research

The aim of this study is to investigate the incidence of macular degeneration and its related influencing factors in the population undergoing physical examinations. 12638 subjects who underwent health examinations at our hospital's physical examination center from January 2018 to December 2022 were selected as the research subjects. Their demographic data, medical history, lifestyle habits, and ophthalmic examination data were collected. Univariate analysis and multivariate logistic regression models were used to screen for relevant factors of macular degeneration. [1] The results showed that among 12638 examinees, 896 cases of macular degeneration were detected, with a prevalence rate of 7.09%. Multivariate analysis showed that age ≥ 60 (OR=3.21, 95% CI: 2.15-4.79), history of diabetes (OR=2.83, 95% CI: 1.76-4.55), history of hypertension (OR=2.17, 95% CI: 1.42-3.31), long-term smoking (OR=1.98, 95% CI: 1.29-3.04), and daily use of electronic equipment ≥ 4 hours (OR=1.65, 95% CI: 1.08-2.52) were independent risk factors for macular degeneration; Exercise ≥ 3 times a week (OR=0.58, 95% CI: 0.39-0.86) is a protective factor. The conclusion indicates that macular degeneration has a certain prevalence in the physical examination population and is related to multiple factors. Targeted intervention can reduce the risk of onset.

Physical examination population; Macular disease; Risk factors; Correlation analysis