Journal of International Psychiatry

【Abstract】Objective To study the buspirone in the treatment of schizophrenia patients with pathological or drugs-induced efficacy of anxiety. Methods Selected in December 2014 to December 2016 in our income treatment of schizophrenia patients with pathological or drugs-induced anxiety with 110 cases to carry out the investigation and study, according to different clinical treatment plan is divided into the treatment group and control group (n = 55), control group, with antipsychotic drug therapy, treatment group in the control group treated with buspirone, comparing the effect after treatment. Results After treatment, the treatment group BPRS score of anxiety depression, lack of energy, thought disorder, activation, hostile suspicion score lower than the control group, the PANSS score lower than the control group. The TESS score of the treatment group was significantly lower than the reference group (P<0.05) in the sixth and eighth weeks of treatment with TESS score. The HAMA score of the treatment group was faster than that of the reference group (P<0.05) from second weeks. The effective rate of the treatment group (94.5%) was significantly higher than that of the reference group (76.4%) (P<0.05). Conclusion Buspirone in the treatment of schizophrenia can quickly relieve patients mental symptoms, relieve anxiety and high security.

【Key words】Buspirone. Antipsychotic drugs; Schizophrenia; anxiety