西酞普兰和心理干预对治疗抑郁症患者躯体症状及认知功能的影响

Analysis on the Influence of Citalopram and Psychological Intervention for the Treatment of Depression Patients with Somatic Symptoms and Cognitive Function

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(4)
作者
作者单位

新疆维吾尔自治区人民医院临床心理科 ;

摘要
摘要:目的:观察和分析草酸艾司西酞普兰和心理干预治疗抑郁症患者的临床疗效和治疗的安全性以及各种不良反应情况,及对患者躯体症状及认知功能的影响。方法:选取2014年6月到2016年12月我院收治的64例抑郁症患者,按照不同治疗方法分成两组,其中对照组32例采用草酸艾司西酞普兰治疗,研究组32例采用草酸艾司西酞普兰和心理干预进行治疗。进行2个月治疗,观察两组患者治疗前及治疗后1,4,8周的临床效果,采用汉密尔顿抑郁量表(HAMD)对治疗的结果和安全性进行评定,并运用副反应量表(TESS))评定药物不良反应。结果:通过治疗后,两组患者与治疗前相比,HAMD评分均下降,且与对照组相比,治疗后的HAMD评分低于对照组,明显差异具有统计意义(P均<0.05);研究组较对照组不良反应少,并且研究组具有更好的耐受性,明显差异具有统计意义(P<0.05)。护理前,各项指标评分无显著差异(P>0.05),护理后,研究组的躯体功能、机体疼痛、社会功能指标显著高于对照组,组间差异显著(P<0.05),一般健康状况、心理健康两项指标略高于对照组,差异不显著(P>0.05)。结论:通过对抑郁症患者采用草酸艾司西酞普兰和心理干预治疗,疗效明显,耐受性好,患者依从性相对较高,且不良反应较少,值得临床推广应用。
Abstract
Abstract: Objective: To observe and analyze escitalopram citalopram and psychological intervention in treatment of depression in patients with clinical efficacy and the safety of the therapy and all kinds of adverse reactions, and the effects on the body symptoms and cognitive function in patients with. Methods: From June 2014 to December 2016 of our hospital, 64 cases of patients with depression, according to the different treatment methods were divided into two groups, control group, 32 cases with venlafaxine, drug treatment group 32 cases with escitalopram citalopram and psychological intervention treatment. For 2 months of treatment, observe two groups of patients before and after treatment 1, 4, 8 weeks clinical effect, the Hamilton depression rating scale (HAMD) and the results of treatment of safety evaluation, and USES symptoms scale (TESS) to evaluate the adverse drug reactions. Results: After treatment, two groups of patients compared with before treatment, HAMD scores decreased, and compared with control group, the HAMD score lower than the control group after treatment, significant differences statistically significant (P < 0.05); Team was less adverse reaction, and the team has better tolerability, significant differences statistically significant (P < 0.05). 8 weekend NOSIE scores when the team is better than that of control group (P < 0.05). Conclusion: By using escitalopram citalopram in patients with senile depression and psychological intervention treatment, obvious curative effect, good tolerance, patient compliance is relatively high, and with less adverse reactions, worthy of clinical popularization and application.
关键词
关键词:草酸艾司西酞普兰;老年抑郁症;疗效;安全性
KeyWord
Key words:Escitalopram Oxalate Tablets;Geriatric depression; Curative effect; Security
基金项目
页码 625-627
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古力巴克然木•阿布拉,胡曼娜,马瑞,邹韶红*. 西酞普兰和心理干预对治疗抑郁症患者躯体症状及认知功能的影响 [J]. 国际精神病学杂志. 2017; 44; (4). 625 - 627.

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