Journal of International Psychiatry

【Abstract】 Objective To investigate the clinical characteristics of patients with first-episode post-stroke depression and analyze the relationship between disease and lesion.Methods in our hospital from December 2014 to early December 2016 in our hospital 68 cases of cerebral infarction in patients with stroke, according to whether the patients with depression were divided into: 21 patients with depression, as observation group, 47 cases without depression, as control group, observe two groups of patients with clinical features and analysis of focal brain infarction after stroke and depression lesion size, correlation.Results the two groups of patients with left hemisphere infarction rate comparison, there were significant differences in subcortical and frontal lobe infarction (P < 0.05), right hemisphere infarction rate was no significant difference (P > 0.05); the observation group the infarct size was larger than 3.6cm proportion of patients was significantly higher than that of control group, the difference was statistically significant (P < 0.05); in the observation group were larger than 3.6cm in diameter in patients with severe depression was significantly higher than the diameter less than 3.6cm group, compared with statistical difference existed between groups (P < 0.05).Conclusion the incidence of cerebral infarction in patients with post stroke depression is common in the left hemisphere cortex, and the severity of post-stroke depression is closely related to the size of the infarct size.

【Key words】 first cerebral infarction; poststroke depression; clinical features; correlation