Journal of International Psychiatry

【Abstract】 Objective: Patients with cryptogenic stroke complicated with patent foramen ovale are often accompanied by a series of psychological symptoms. The aim of this study was to assess changes in depression and anxiety levels in patients before and after closure. Methods: From January 2011 to December 2014, 80 patients with cryptogenic hemorrhage complicated with patent for vaginal cavity were enrolled in the Department of Cardiac Surgery. The depression and anxiety levels of patients before and after surgery were assessed by the Znug Depression Rating Scale (SDS) and the Znug Anxiety Rating Scale (SAS). Results: A total of 80 patients completed SDS and SAS evaluation. Most patients have a certain degree of depression and anxiety before surgery. The severity of depression and anxiety was significantly reduced after surgery; the mean scores of SDS and SAS decreased from moderate to normal (P <0.001). SDS and SAS were the independent predictors of postoperative improvement (P <0.001). Female patients had a significantly lower preoperative SDS score (P = .005) but improved postoperative (P = .012). Conclusion: Depression and anxiety are common problems in patients with cryptogenic stroke complicated with patent foramen ovale, and blockade can effectively improve depression and anxiety symptoms.

【Key words】 cryptogenic stroke; patent foramen ovale; occlusion; depression; anxiety disorder