International Journal of Nursing Research

Objective To assess the current clinical status of prevention and management of Central line-associated bloodstream infection (CLABSI) in pediatric non-ICU patients, analyze the barriers in the evidence-based practice process, and explore corresponding strategies. Methods Evidence was reviewed and summarized to establish audit criteria. Following a baseline audit, barriers were analyzed using the i-PARIHS model. Results The baseline audit revealed that compliance for 19 out of 24 indicators was below 90%, with 3 indicators showing 0% compliance. Analysis using the i-PARIHS model identified key barriers across three domains: (1) Innovation : Insufficient localization of evidence (e.g., antibiotic lock therapy) and a lack of standardized procedures and tools (e.g., catheterization checklists); (2) Recipients : Inadequate knowledge updates among healthcare workers, perceptual biases regarding procedures, and limited effectiveness of patient education; (3) Organizational environment : Failure to routinely integrate critical procedures (e.g., isolating stoma care from catheter manipulation, daily catheter assessment), coupled with insufficient material support and inadequate multidisciplinary evaluation mechanisms. Conclusion Multiple barriers hinder evidence-based practice in CLABSI prevention and management in pediatric non-ICU patients. Developing strategies focused on the recipients of change and establishing effective incentive and feedback mechanisms are essential to promote the translation of best evidence into clinical practice.

Central line-associated bloodstream infection; i-PARIHS model; Pediatrics; Non-ICU; Evidence-based; Barrier analysis